A-CHMINACA

Synthetic cannabinoid From Wikipedia, the free encyclopedia

A-CHMINACA, (ACHMINACA, Adamantyl-CHMINACA, SGT-37), is an indazole-based synthetic cannabinoid that binds to the CB1 and CB2 receptors.[2][3]

Legal status
  • DE: NpSG (Industrial and scientific use only)[a]
Quick facts Legal status, Identifiers ...
A-CHMINACA
Legal status
Legal status
  • DE: NpSG (Industrial and scientific use only)[a]
Identifiers
  • N-(1-adamantyl)-1-(cyclohexylmethyl)indazole-3-carboxamide
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC25H33N3O
Molar mass391.559 g·mol−1
3D model (JSmol)
  • C1CCC(CC1)CN2C3=CC=CC=C3C(=N2)C(=O)NC45CC6CC(C4)CC(C6)C5
  • InChI=1S/C25H33N3O/c29-24(26-25-13-18-10-19(14-25)12-20(11-18)15-25)23-21-8-4-5-9-22(21)28(27-23)16-17-6-2-1-3-7-17/h4-5,8-9,17-20H,1-3,6-7,10-16H2,(H,26,29)
  • Key:ACFKPINHOINOFB-UHFFFAOYSA-N
Close

It has an EC50 of 159 nM for human CB1 receptors.[4]

Metabolism

A-CHMINACA is not hydrolized by human carboxylesterases which increases its half-life.[5]

Distribution

A-CHMINACA has been sold as a designer drug with one sample having been seized by Polish authorities in Lublin.[6]

It was also detected in samples taken in Toronto in 2020.[7]

See also

References

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