AB-CHFUPYCA

AB-CHFUPYCA (also AB-CHMFUPPYCA)^[1] is a compound that was first identified as a component of synthetic cannabis products in Japan in 2015.^[2][3] The name "AB-CHFUPYCA" is an acronym of its systematic name N-(1-Amino-3-methyl-1-oxoButan-2-yl)-1-(CycloHexylmethyl)-3-(4-FlUorophenyl)-1H-PYrazole-5-CarboxAmide. There are two known regioisomers of AB-CHFUPYCA: 3,5-AB-CHMFUPPYCA (pictured) and 5,3-AB-CHMFUPPYCA.^[4] The article[1] refers to both 3,5-AB-CHMFUPPYCA and 5,3-AB-CHMFUPPYCA as AB-CHMFUPPYCA isomers, so AB-CHMFUPPYCA and AB-CHFUPYCA are not names for a unique chemical structure.

Legal status

• CA: Schedule II
• DE: NpSG (Industrial and scientific use only)
• UK: Under Psychoactive Substances Act

CAS Number

• 1870799-79-3 ^Y

PubChem CID

• 122213879

ChemSpider

• 67168777

Quick facts Legal status, Identifiers ...

AB-CHFUPYCA

Legal status
Legal status	CA: Schedule II DE: NpSG (Industrial and scientific use only) UK: Under Psychoactive Substances Act
Identifiers
IUPAC name N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(cyclohexylmethyl)-3-(4-fluorophenyl)-1H-pyrazole-5-carboxamide
CAS Number	1870799-79-3 Y
PubChem CID	122213879
ChemSpider	67168777
UNII	O4PS4BDB8K
CompTox Dashboard (EPA)	DTXSID401009994
Chemical and physical data
Formula	C22H29FN4O2
Molar mass	400.498 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C(NC(C(N)=O)C(C)C)C1=CC(C2=CC=C(F)C=C2)=NN1CC3CCCCC3
InChI InChI=1S/C22H29FN4O2/c1-14(2)20(21(24)28)25-22(29)19-12-18(16-8-10-17(23)11-9-16)26-27(19)13-15-6-4-3-5-7-15/h8-12,14-15,20H,3-7,13H2,1-2H3,(H2,24,28)(H,25,29) Key:NDYOOVJIZQTGHY-UHFFFAOYSA-N

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AB-CHFUPYCA contains some similar structural elements to other synthetic cannabinoids such as 5F-AB-FUPPYCA, JWH-307, JWH-030, JWH-147, AB-PINACA. It may be considered an analog of the traditional pyrazole cannabinoid receptor 1 antagonist rimonabant. The pharmacological properties of AB-CHFUPYCA have not been studied.