ABLIM1

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Actin binding LIM protein 1, also known as ABLIM1, is a protein which in humans is encoded by the ABLIM1 gene.[5][6]

AliasesABLIM1, ABLIM, LIMAB1, LIMATIN, abLIM-1, actin binding LIM protein 1
End114,768,061 bp[1]
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ABLIM1
Identifiers
AliasesABLIM1, ABLIM, LIMAB1, LIMATIN, abLIM-1, actin binding LIM protein 1
External IDsOMIM: 602330; MGI: 1194500; HomoloGene: 40994; GeneCards: ABLIM1; OMA:ABLIM1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)
RefSeq (protein)
Location (UCSC)Chr 10: 114.43 – 114.77 MbChr 19: 57.02 – 57.3 Mb
PubMed search[3][4]
Wikidata
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Function

This gene encodes a cytoskeletal LIM protein that binds to actin filaments via a domain that is homologous to erythrocyte dematin. LIM domains, found in over 60 proteins, play key roles in the regulation of developmental pathways. LIM domains also function as protein-binding interfaces, mediating specific protein-protein interactions. The protein encoded by this gene could mediate such interactions between actin filaments and cytoplasmic targets. Alternatively spliced transcript variants encoding different isoforms have been identified.[5]

Interactions

ABLIM1 has been shown to interact with LDOC1.[7]

References

Further reading

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