BOH-2C-B
Chemical compound
From Wikipedia, the free encyclopedia
BOH-2C-B, or BOHB, also known as 4-bromo-2,5-dimethoxy-β-hydroxyphenethylamine or as β-hydroxy-2C-B, is a psychedelic drug of the phenethylamine, 2C, and BOx families.[2] It is the β-hydroxy derivative of 2C-B.[2] The drug has been encountered as a novel designer drug.[3][4]
- DE: NpSG (Industrial and scientific use only)
- UK: Under Psychoactive Substances Act
- Illegal in Netherlands
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| Other names | BOH-2C-B-; BOHB; β-Hydroxy-4-bromo-2,5-dimethoxyphenethylamine; β-Hydroxy-2C-B; β-OH-2C-B |
| Routes of administration | Oral[1] |
| Drug class | Serotonin 5-HT2 receptor agonist; Serotonin 5-HT2A receptor agonist; Serotonergic psychedelic; Hallucinogen |
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| Onset of action | Unknown[1] |
| Duration of action | Unknown[1] |
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| Formula | C10H14BrNO3 |
| Molar mass | 276.130 g·mol−1 |
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Use and effects
BOH-2C-B was not included or mentioned in Alexander Shulgin's book PiHKAL (Phenethylamines I Have Known and Loved).[5] Subsequently, Daniel Trachsel listed BOHB's dose as 30 mg or more orally in his book Phenethylamine: von der Struktur zur Funktion (Phenethylamines: From Structure to Function).[1]
Interactions
Pharmacology
Chemistry
BOH-2C-B is a substituted phenethylamine.[2] It features methoxy substituents at the 2- and 5-position of the ring, as well as a bromine at the 4-position.[2] A hydroxy group is present at the beta (β) position from the functional amine group connected to the alpha (α) carbon, giving rise to its name.[2]
Analogues
Analogues of BOH-2C-B include 2C-B, BOB (β-methoxy-2C-B), βk-2C-B (β-keto-2C-B), β-methyl-2C-B, BOHD (β-hydroxy-2C-D), and BOD (β-methoxy-2C-D), among others.[5]
History
BOH-2C-B was first described in a 2004 study by Richard Glennon and colleagues on the optimization of phenethylamine 5-HT2A serotonin receptor agonists, although it is not mentioned by name.[2] It was encountered as a novel designer drug in 2019.[3][4] However, it is said to have been on the market since 2015.[4]
Society and culture
Legal status
BOH-2C-B is a controlled substance in the following countries:
- Canada: BOH-2C-B is a controlled substance under phenethylamine blanket-ban language.[7]
- Germany: BOH-2C-B is controlled under the New Psychoactive Substances Act (NpSG) as of November 26, 2016. Possession is illegal but not penalized.[8]
- Netherlands:: BOH-2C-B is not specifically scheduled in the NL but may be considered a ring-derived analogue of 2-phenethylamine which would make it illegal under updates made to the Dutch Opium Act in February 2024.[9]
- United Kingdom: BOH-2C-B is illegal to produce, supply or import under the Psychoactive Substance Act as of May 26, 2016.[10]
- United States: BOH-2C-B is unscheduled in the U.S., but may be considered an analogue of 2C-B under the Federal Analogue Act, and thus a Schedule I drug.[11]