GRAM domain
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| GRAM domain | |||||||||
|---|---|---|---|---|---|---|---|---|---|
Myotubularin-related protein 2 | |||||||||
| Identifiers | |||||||||
| Symbol | GRAM | ||||||||
| Pfam | PF02893 | ||||||||
| Pfam clan | CL0266 | ||||||||
| InterPro | IPR004182 | ||||||||
| SMART | GRAM | ||||||||
| SCOP2 | 1lw3 / SCOPe / SUPFAM | ||||||||
| OPM superfamily | 130 | ||||||||
| OPM protein | 1zvr | ||||||||
| CDD | cd10570 | ||||||||
| Membranome | 349 | ||||||||
| |||||||||
The GRAM domain is found in glucosyltransferases, myotubularins and other membrane-associated proteins.[1] The structure of the GRAM domain is similar to that found in PH domains.[2]
Proteins containing GRAM domains are found in all eukaryotes and bacteria, but not archaea.[3] Various GRAM domains can bind proteins or lipids.[3]