HLA-DR52
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major histocompatibility complex, class II, DR53 | ||
| Haplotypes groups | DRA*01:DRB3*01 DRA*01:DRB3*02 DRA*01:DRB3*03 | |
| Structure (See HLA-DR) | ||
| Identifiers | alpha *01:01 | |
| Symbol(s) | HLA-DRA[permanent dead link] | |
| EBI-HLA | DRA*01:01 | |
| Identifiers | beta 3 *01 *02 *03 | |
| Symbol(s) | HLA-DRB3[permanent dead link] | |
| EBI-HLA | DRB3*01 | |
| EBI-HLA | DRB3*02 | |
| EBI-HLA | DRB3*03 Archived 2011-05-15 at the Wayback Machine | |
| Shared data | ||
| Locus | chr.6 6p21.31 | |
HLA-DR52 is an HLA-DR serotype that recognizes gene products of HLA-DRB3 locus. Three allele groups can produce 35 isoforms.
DRB3, DRB4, and DRB5 are minor DR beta-encoding loci, and they have been recognized as having distinct evolution,[1] having diverged from DRB1 around 4 million years ago.[2]
The DRB3 locus is only apparent in a small subset of DR haplotypes, and most individuals lack DRB3.