JNJ-10397049

JNJ-10397049
Clinical data
ATC code	none;
Identifiers
	IUPAC name 1-(2,4-dibromophenyl)-3-((4S,5S)-2,2-dimethyl-4-phenyl-1,3-dioxan-5-yl)urea;
CAS Number	708275-58-5 ;
PubChem CID	9869934;
IUPHAR/BPS	1701;
ChemSpider	8045625 ;
UNII	1B419P24AV;
ChEMBL	ChEMBL359632;
CompTox Dashboard (EPA)	DTXSID501336831 ;
Chemical and physical data
Formula	C19H20Br2N2O3
Molar mass	484.188 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES BrC1=CC=C(NC(N[C@@H]2[C@H](C3=CC=CC=C3)OC(C)(C)OC2)=O)C(Br)=C1;
	InChI InChI=1S/C19H20Br2N2O3/c1-19(2)25-11-16(17(26-19)12-6-4-3-5-7-12)23-18(24)22-15-9-8-13(20)10-14(15)21/h3-10,16-17H,11H2,1-2H3,(H2,22,23,24)/t16-,17-/m0/s1 ; Key:RBKIJGLHFFQHBE-IRXDYDNUSA-N ;

JNJ-10397049 is a potent and highly selective OX₂ receptor antagonist. In animals, JNJ-10397049 was found to have sleep-promoting effects and to attenuate the reinforcing effects of ethanol.^[1]^[2]

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