KH-3 (drug)

CAS Number

• 1215115-03-9

PubChem CID

• 45138018

ChemSpider

• 114849422

ChEMBL

• ChEMBL5404494

KH-3 (drug)

Identifiers
IUPAC name (E)-3-[5-[(4-tert-butylphenyl)sulfonylamino]-1-benzothiophen-2-yl]-N-hydroxyprop-2-enamide
CAS Number	1215115-03-9
PubChem CID	45138018
ChemSpider	114849422
ChEMBL	ChEMBL5404494
Chemical and physical data
Formula	C21H22N2O4S2
Molar mass	430.54 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)NC2=CC3=C(C=C2)SC(=C3)/C=C/C(=O)NO
InChI InChI=1S/C21H22N2O4S2/c1-21(2,3)15-4-8-18(9-5-15)29(26,27)23-16-6-10-19-14(12-16)13-17(28-19)7-11-20(24)22-25/h4-13,23,25H,1-3H3,(H,22,24)/b11-7+ Key:RIYPLPNXICDUCS-YRNVUSSQSA-N

KH-3 is an experimental drug which acts as an inhibitor of the RNA-binding HuR protein. Elevated levels of HuR are found in many forms of cancer, and KH-3 is being researched for potential applications in cancer treatment.^{[1][2][3][4][5][6][7][8]}