Miricorilant

Chemical compound From Wikipedia, the free encyclopedia

Miricorilant (CORT-118335) is a small molecule that works as a selective glucocorticoid receptor modulator and mineralcorticoid receptor antagonist.[1][2][3][4] It was developed by Corcept Therapeutics for nonalcoholic steatohepatitis[5] and weight gain associated with atypical antipsychotics.[6]

Other namesCORT-118335
Legal status
  • Investigational
Quick facts Clinical data, Other names ...
Miricorilant
Clinical data
Other namesCORT-118335
Legal status
Legal status
  • Investigational
Identifiers
  • trans-6-(4-phenylcyclohexyl)-5-[[3-(trifluoromethyl)phenyl]methyl]-1H-pyrimidine-2,4-dione
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
Chemical and physical data
FormulaC24H23F3N2O2
Molar mass428.455 g·mol−1
3D model (JSmol)
  • C1CC(CCC1C2=CC=CC=C2)C3=C(C(=O)NC(=O)N3)CC4=CC(=CC=C4)C(F)(F)F
  • InChI=1/C24H23F3N2O2/c25-24(26,27)19-8-4-5-15(13-19)14-20-21(28-23(31)29-22(20)30)18-11-9-17(10-12-18)16-6-2-1-3-7-16/h1-8,13,17-18H,9-12,14H2,(H2,28,29,30,31)/t17-,18-
  • Key:GVVUZBSCYAVFTI-IYARVYRRNA-N
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