Percavirus
Genus of viruses
From Wikipedia, the free encyclopedia
Percavirus is a genus of viruses in the order Herpesvirales, in the family Herpesviridae, in the subfamily Gammaherpesvirinae. Mammals serve as natural hosts. Diseases associated with this genus include: conjunctivitis, immunosuppression in foals, pneumonia, respiratory disease.[1][2]
| Percavirus | |
|---|---|
Virus classification  | |
| (unranked): | Virus |
| Realm: | Duplodnaviria |
| Kingdom: | Heunggongvirae |
| Phylum: | Peploviricota |
| Class: | Herviviricetes |
| Order: | Herpesvirales |
| Family: | Orthoherpesviridae |
| Subfamily: | Gammaherpesvirinae |
| Genus: | Percavirus |
| Species | |
|
See text | |
Species
The genus consists of the following species:[2]
- Percavirus equidgamma2, also called Equid gammaherpesvirus 2
- Percavirus equidgamma5, also called Equid gammaherpesvirus 5
- Percavirus felidgamma1, also called Felid gammaherpesvirus 1
- Percavirus mustelidgamma1, also called Mustelid gammaherpesvirus 1
- Percavirus phocidgamma3, also called Phocid gammaherpesvirus 3
- Percavirus rhinolophidgamma1
- Percavirus vespertilionidgamma1, also called Vespertilionid gammaherpesvirus 1
Structure
Viruses in Percavirus are enveloped, with icosahedral, spherical to pleomorphic, and round geometries, and T=16 symmetry. The diameter is around 150-200 nm. Genomes are linear and non-segmented, around 180kb in length.[1]
| Genus | Structure | Symmetry | Capsid | Genomic arrangement | Genomic segmentation |
|---|---|---|---|---|---|
| Percavirus | Spherical pleomorphic | T=16 | Enveloped | Linear | Monopartite |
Life cycle
Viral replication is nuclear, and is lysogenic. Entry into the host cell is achieved by attachment of the viral glycoproteins to host receptors, which mediates endocytosis. Replication follows the dsDNA bidirectional replication model. DNA-templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear egress, and budding. Mammals serve as the natural host.[1]
| Genus | Host details | Tissue tropism | Entry details | Release details | Replication site | Assembly site | Transmission |
|---|---|---|---|---|---|---|---|
| Percavirus | Mammals | B-lymphocytes | Glycoprotiens | Budding | Nucleus | Nucleus | Sex; saliva |
