Phenflutermine

Phenflutermine, also known as 3-trifluoromethyl-N-ethyl-α-methylamphetamine or as 3-trifluoromethyl-N-ethylphentermine, is a chemical compound of the phenethylamine, amphetamine, and phentermine families.^[1] It is the combined or hybrid derivative of the fenfluramine and phentermine, which were used together in the withdrawn combination anorectic fenfluramine/phentermine (Fen-Phen).^[1] The compound was first described in the scientific literature by Daniel Trachsel in his book on phenethylamines in 2013.^[1] It is not known to have been synthesized, tested, or otherwise described in the literature.^[1] However, both fenfluramine and phentermine are known to act as monoamine releasing agents and to have anorectic effects.^[2][3]

Other namesPhenflutermin; 3-Trifluoromethyl-N-ethyl-α-methylamphetamine; 3-Trifluoromethyl-N-ethylphentermine; N-Ethyl-α,α-dimethyl-3-trifluoromethylphenethylamine; N-Et-α,α-Me-3-TFMPEA; Fenflutermine

ATC code

• None

FormulaC₁₃H₁₈F₃N

Molar mass245.289 g·mol⁻¹

Quick facts Clinical data, Other names ...

Phenflutermine

Clinical data
Other names	Phenflutermin; 3-Trifluoromethyl-N-ethyl-α-methylamphetamine; 3-Trifluoromethyl-N-ethylphentermine; N-Ethyl-α,α-dimethyl-3-trifluoromethylphenethylamine; N-Et-α,α-Me-3-TFMPEA; Fenflutermine
ATC code	None
Identifiers
IUPAC name N-ethyl-2-methyl-1-[3-(trifluoromethyl)phenyl]propan-2-amine
Chemical and physical data
Formula	C13H18F3N
Molar mass	245.289 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCNC(C)(C)CC1=CC(C(F)(F)F)=CC=C1
InChI InChI=1S/C13H18F3N/c1-4-17-12(2,3)9-10-6-5-7-11(8-10)13(14,15)16/h5-8,17H,4,9H2,1-3H3 Key:DRSIPICEAYYBGT-UHFFFAOYSA-N

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