TLX1

TLX1
Identifiers
Aliases	TLX1, HOX11, TCL3, T-cell leukemia homeobox 1, T cell leukemia homeobox 1
External IDs	OMIM: 186770; MGI: 98769; HomoloGene: 4031; GeneCards: TLX1; OMA:TLX1 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	101,137,789 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	45,145,382 bp
RNA expression pattern
	Top expressed in
	spleen; ; testicle; ; minor salivary glands; ; gonad; ; right lobe of liver; ; mucosa of transverse colon; ; duodenum; ; tonsil; ; ventricle of the heart; ; left ventricle;
	Top expressed in
	dorsal mesentery; ; tongue; ; middle ear; ; submandibular gland; ; outer ear; ; auricle; ; skin of external ear; ; female urethra; ; male urethra; ; Eustachian tube;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA binding; sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; protein binding; DNA-binding transcription factor activity, RNA polymerase II-specific; DNA-binding transcription factor activity;
Cellular component	nucleus;
Biological process	multicellular organism development; regulation of transcription, DNA-templated; transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	3195
	21908
	ENSG00000107807
	ENSMUSG00000025215
	P31314
	P43345
	NM_001195517; NM_005521
	NM_021901
	NP_001182446; NP_005512
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

T-cell leukemia homeobox protein 1 is a protein that in humans is encoded by the TLX1 gene, which was initially named HOX11.^[5]^[6]^[7]^[8]^[9]