TRPM2

TRPM2
Identifiants
Alias	TRPM2
IDs externes	OMIM: 603749 MGI: 1351901 HomoloGene: 20709 GeneCards: TRPM2
Position du gène (humain)
Chr.	Chromosome 21 humain
Fin	44,443,081 bp
Position du gène (souris)
Chr.	Chromosome 10 (souris)
Fin	77,970,563 bp
Expression génique
	Fortement exprimé dans
	right frontal lobe; ; noyau caudé; ; noyau accumbens; ; monocyte; ; putamen; ; gyrus cingulaire; ; Brodmann area 9; ; cortex cingulaire antérieur; ; granulocyte; ; right hemisphere of cerebellum;
	Fortement exprimé dans
	granulocyte; ; lumbar subsegment of spinal cord; ; ganglion mésentérique; ; rate; ; primary visual cortex; ; gyrus frontal supérieur; ; dentate gyrus of hippocampal formation granule cell; ; cerebellar cortex; ; sang; ; moelle osseuse;
	Plus de données d'expression de référence
	n/a
Gene Ontology
Fonction moléculaire	calcium channel activity; sodium channel activity; ion channel activity; cation channel activity; calcium liaison ionique; calcium-release channel activity; activité hydrolase; ligand-gated calcium channel activity; liaison ion métal; ADP-ribose diphosphatase activity; mono-ADP-D-ribose binding;
Composant cellulaire	integral component of membrane; membrane; membrane plasmique; lysosome; lysosomal membrane; integral component of plasma membrane; membrane d'une vésicule cytoplasmique; vésicule cytoplasmique; specific granule membrane; prolongement cellulaire; péricaryon; tertiary granule membrane; ficolin-1-rich granule membrane;
Processus biologique	sodium ion transmembrane transport; sodium ion transport; cation transport; ion transport; response to oxidative stress; calcium ion transmembrane transport; calcium ion transport; ion transmembrane transport; transport transmembranaire; temperature homeostasis; dendritic cell chemotaxis; response to purine-containing compound; calcium-mediated signaling using intracellular calcium source; neutrophil degranulation; release of sequestered calcium ion into cytosol; regulation of filopodium assembly; cellular response to hydrogen peroxide; cellular response to calcium ion; cellular response to purine-containing compound; cellular response to temperature stimulus; zinc ion transmembrane transport; dendritic cell differentiation; calcium ion transmembrane import into cytosol; regulation of actin cytoskeleton reorganization; calcium ion import across plasma membrane; protein homotetramerization;
	Sources:Amigo / QuickGO
Orthologues
	7226
	28240
	ENSG00000142185
	ENSMUSG00000009292
	O94759
	Q91YD4
	NM_001001188; NM_003307; NM_001320350; NM_001320351; NM_001320352
	NM_138301
	NP_001307279; NP_001307280; NP_001307281; NP_003298
	NP_612174
	Wikidata
Voir/Editer Humain	Voir/Editer Souris

Le TRPM2 (« Transient receptor potential cation channel, subfamily M, member 2 ») est une protéine, de type canal calcique dont le gène est TRPM2 situé sur le chromosome 21 humain.

AliasTRPM2

IDs externesOMIM: 603749 MGI: 1351901 HomoloGene: 20709 GeneCards: TRPM2

Chr.Chromosome 21 humain^[1]

Fin44,443,081 bp^[1]

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