2018 CDMX Open

Country	Player	Rank1	Seed
GER	Yannick Hanfmann	121	1
BRA	Thiago Monteiro	125	2
ARG	Carlos Berlocq	131	3
ESP	Adrián Menéndez Maceiras	140	4
GER	Mats Moraing	156	5
DOM	Víctor Estrella Burgos	160	6
ESA	Marcelo Arévalo	175	7
SRB	Peđa Krstin	206	8

• ¹ Rankings are as of 2 April 2018.^[1]

The following players received wildcards into the singles main draw:

• Lucas Gómez
• Sebastian Korda
• Luis Patiño
• Manuel Sánchez

The following player received entry into the singles main draw as a special exempt:

• Carlos Berlocq

The following players received entry from the qualifying draw:

• Andrea Basso
• José Hernández-Fernández
• Austin Krajicek
• Juan Ignacio Londero

• Juan Ignacio Londero def. Roberto Quiroz 6–1, 6–3.

• Yannick Hanfmann / Kevin Krawietz def. Luke Bambridge / Jonny O'Mara 6–2, 7–6^(7–3).