2018 Las Vegas Challenger

Country	Player	Rank1	Seed
RSA	Lloyd Harris	112	1
ESP	Adrián Menéndez Maceiras	122	2
NOR	Casper Ruud	127	3
TPE	Jason Jung	128	4
USA	Noah Rubin	129	5
USA	Reilly Opelka	132	6
GER	Dominik Köpfer	175	7
ESA	Marcelo Arévalo	181	8

• ¹ Rankings are as of October 15, 2018.^[1]

The following players received wildcards into the singles main draw:

• Alexander Cozbinov
• Evan Song
• Mikael Torpegaard
• J. J. Wolf

The following player received entry into the singles main draw as a special exempt:

• Borna Gojo

The following player received entry into the singles main draw as an alternate:

• Jan Choinski

The following players received entry from the qualifying draw:

• Mathias Bourgue
• Thai-Son Kwiatkowski
• Roberto Ortega Olmedo
• Tommy Paul

The following players received entry as lucky losers:

• Evan King
• Alexander Sarkissian
• Jelle Sels

• Thanasi Kokkinakis def. Blaž Rola 6–4, 6–4.

• Marcelo Arévalo / Roberto Maytín def. Robert Galloway / Nathan Pasha 6–3, 6–3.