2018 Tashkent Challenger

Country	Player	Rank1	Seed
BIH	Mirza Bašić	77	1
UZB	Denis Istomin	103	2
ESP	Enrique López Pérez	167	3
CZE	Lukáš Rosol	177	4
RUS	Alexey Vatutin	178	5
POL	Kamil Majchrzak	181	6
GER	Daniel Brands	185	7
EGY	Mohamed Safwat	196	8

• ¹ Rankings are as of 1 October 2018.^[1]

The following players received wildcards into the singles main draw:

• Alen Avidzba
• Jurabek Karimov
• Khumoyun Sultanov
• Dimitriy Voronin

The following player received entry into the singles main draw using a protected ranking:

• Egor Gerasimov

The following players received entry from the qualifying draw:

• Félix Auger-Aliassime
• Mathias Bourgue
• Frederico Ferreira Silva
• Rubin Statham

The following player received entry as a lucky loser:

• Roman Safiullin

• Félix Auger-Aliassime def. Kamil Majchrzak 6–3, 6–2.

• Sanjar Fayziev / Jurabek Karimov def. Federico Gaio / Enrique López Pérez 6–2, 6–7^(3–7), [11–9].