2018 Puerto Vallarta Open

Country	Player	Rank1	Seed
ESP	Adrián Menéndez Maceiras	151	1
DOM	Víctor Estrella Burgos	168	2
USA	Kevin King	173	3
USA	Christopher Eubanks	246	4
SRB	Danilo Petrović	247	5
USA	Alexander Sarkissian	257	6
DOM	José Hernández-Fernández	261	7
ECU	Roberto Quiroz	280	8

• ¹ Rankings are as of 23 April 2018.^[2]

The following players received wildcards into the singles main draw:

• Tigre Hank
• Gerardo López Villaseñor
• Manuel Sánchez
• Marcelo Sepúlveda

The following players received entry into the singles main draw using protected rankings:

• Nicolás Barrientos
• Alejandro Gómez

The following player received entry into the singles main draw as an alternate:

• Brydan Klein

The following players received entry from the qualifying draw:

• Viktor Durasovic
• Felipe Mantilla
• Luis David Martínez
• Evan Song

• Adrián Menéndez Maceiras def. Danilo Petrović 1–6, 7–5, 6–3.

• Ante Pavić / Danilo Petrović def. Benjamin Lock / Fernando Romboli 6–7^(2–7), 6–4, [10–5].