2024 Uruguay Open

Country	Player	Rank1	Seed
ARG	Francisco Comesaña	99	1
BRA	Thiago Monteiro	100	2
ARG	Federico Coria	103	3
ARG	Camilo Ugo Carabelli	106	4
BOL	Hugo Dellien	125	5
ARG	Román Andrés Burruchaga	131	6
ARG	Federico Agustín Gómez	135	7
ARG	Juan Manuel Cerúndolo	143	8

• ¹ Rankings are as of 4 November 2024.^[1]

The following players received wildcards into the singles main draw:

• Joaquín Aguilar Cardozo
• Genaro Alberto Olivieri
• Franco Roncadelli

The following players received entry from the qualifying draw:

• Mateus Alves
• Luciano Emanuel Ambrogi
• Gastão Elias
• Orlando Luz
• Lautaro Midón
• Gonzalo Villanueva

The following player received entry as a lucky loser:

• Matheus Pucinelli de Almeida

• Tristan Boyer def. Hugo Dellien 6–2, 6–4.

• Guido Andreozzi / Orlando Luz def. Mariano Kestelboim / Franco Roncadelli 4–6, 6–3, [10–8].