ANP32B

Acidic leucine-rich nuclear phosphoprotein 32 family member B (ANP32B) also known as "acidic protein rich in leucines" (APRIL) is a protein that in humans is encoded by the ANP32B gene.^[5][6][7]

PDBOrtholog search: PDBe RCSB

AliasesANP32B, APRIL, PHAPI2, SSP29, acidic nuclear phosphoprotein 32 family member B

External IDsMGI: 1914878; HomoloGene: 21286; GeneCards: ANP32B; OMA:ANP32B - orthologs

Chr.Chromosome 9 (human)^[1]

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ANP32B
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2ELL, 2RR6
Identifiers
Aliases	ANP32B, APRIL, PHAPI2, SSP29, acidic nuclear phosphoprotein 32 family member B
External IDs	MGI: 1914878; HomoloGene: 21286; GeneCards: ANP32B; OMA:ANP32B - orthologs
Gene location (Human) Chr. Chromosome 9 (human)[1] Band 9q22.33 Start 97,983,341 bp[1] End 98,015,943 bp[1]
Gene location (Mouse) Chr. Chromosome 4 (mouse)[2] Band 4|4 B1 Start 46,450,902 bp[2] End 46,472,657 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in tendon of biceps brachii trabecular bone optic nerve thymus internal globus pallidus corpus epididymis cartilage tissue dorsal motor nucleus of vagus nerve parotid gland caput epididymis Top expressed in tail of embryo genital tubercle zygote primary oocyte secondary oocyte bone marrow epiblast yolk sac ventricular zone thymus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function histone binding protein binding RNA polymerase binding Cellular component cytoplasm extracellular exosome nucleolus nucleus Biological process positive regulation of protein export from nucleus negative regulation of cell differentiation inner ear development nucleosome assembly roof of mouth development vasculature development activation of cysteine-type endopeptidase activity involved in apoptotic process ventricular system development histone exchange Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10541 67628 Ensembl ENSG00000136938 ENSMUSG00000028333 UniProt Q92688 Q9EST5 RefSeq (mRNA) NM_006401 NM_130889 RefSeq (protein) NP_006392 NP_570959 Location (UCSC) Chr 9: 97.98 – 98.02 Mb Chr 4: 46.45 – 46.47 Mb PubMed search [3] [4]
Wikidata
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APRIL is also the acronym used for an entirely different protein, TNFSF13, a member of the tumor necrosis factor superfamily whose alternative name, A PRoliferation Inducing Ligand, shares the same acronym as that for ANP32B