ANP32C

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Acidic leucine-rich nuclear phosphoprotein 32 family member C is a protein that in humans is encoded by the ANP32C gene.[2][3][4]

AliasesANP32C, PP32R1, acidic nuclear phosphoprotein 32 family member C
Bgee
HumanMouse (ortholog)
Top expressed in
More reference expression data
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ANP32C
Identifiers
AliasesANP32C, PP32R1, acidic nuclear phosphoprotein 32 family member C
External IDsOMIM: 606877; HomoloGene: 49316; GeneCards: ANP32C; OMA:ANP32C - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_012403
NM_001388483

n/a

RefSeq (protein)

NP_036535

n/a

Location (UCSC)n/an/a
PubMed search[1]n/a
Wikidata
View/Edit Human
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Function

Phosphoprotein 32 (PP32) is a tumor suppressor that can inhibit several types of cancers, including prostate and breast cancers. The protein encoded by this gene is one of at least two proteins that are similar in amino acid sequence to PP32 and are part of the same acidic nuclear phosphoprotein gene family. However, unlike PP32, the encoded protein is tumorigenic. The tumor suppressor function of PP32 has been localized to a 25 amino acid region that is divergent between PP32 and the protein encoded by this gene. This gene does not contain introns.[4]

See also

References

Further reading

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