Casticin

Casticin is a methoxylated flavonol, meaning the core flavonoid structure has methyl groups attached. Found in Artemisia annua, the flavonoid has been shown to enhance the antimalarial activity of artemisinin though casticin itself has no direct antimalarial effects.^[1][2] It has been shown to have anti-mitotic activity. It is also found in Vitex agnus-castus.^[3]

Quick facts Names, Identifiers ...

Casticin

Names
IUPAC name 3′,5-Dihydroxy-3,4′,6,7-tetramethoxyflavone
Systematic IUPAC name 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6,7-trimethoxy-4H-1-benzopyran-4-one
Other names Vitexicarpin
Identifiers
CAS Number	479-91-4 Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:69355
ChEMBL	ChEMBL452767
ChemSpider	4474632
PubChem CID	5315263
UNII	753GT729OU Y
CompTox Dashboard (EPA)	DTXSID80197326
InChI InChI=1S/C19H18O8/c1-23-11-6-5-9(7-10(11)20)17-19(26-4)16(22)14-12(27-17)8-13(24-2)18(25-3)15(14)21/h5-8,20-21H,1-4H3 Key: PJQLSMYMOKWUJG-UHFFFAOYSA-N InChI=1/C19H18O8/c1-23-11-6-5-9(7-10(11)20)17-19(26-4)16(22)14-12(27-17)8-13(24-2)18(25-3)15(14)21/h5-8,20-21H,1-4H3 Key: PJQLSMYMOKWUJG-UHFFFAOYAH
SMILES COC1=C(C=C(C=C1)C2=C(C(=O)C3=C(C(=C(C=C3O2)OC)OC)O)OC)O
Properties
Chemical formula	C19H18O8
Molar mass	374.34 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

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