HLA-A23

From Wikipedia, the free encyclopedia

HLA-A23
(MHC Class I, A cell surface antigen)
HLA-A23
About
Proteintransmembrane receptor/ligand
Structureαβ heterodimer
SubunitsHLA-A*2301, β2-microglobulin
Older namesHL-A9
Subtypes
Subtype
allele
Available structures
A23 *2301
Alleles link-out to IMGT/HLA database at EBI

HLA-A23 (A23) is a human leukocyte antigen serotype within HLA-A serotype group. The serotype is determined by the antibody recognition of α23 subset of HLA-A α-chains. For A23, the alpha, "A", chain are encoded by the HLA-A*23 allele group and the β-chain are encoded by B2M locus.[1] This group currently is dominated by A*2301. A23 and A*23 are almost synonymous in meaning. A23 is a split antigen of the broad antigen HLA-A9 and it is a sister serotype of HLA-A24.

A23 is common in Africa and regions of the Middle East, Mediterranean, and India than Europe, East Asia or the Americas.

A23 recognition of some HLA A*23 gene products[2]
A*23 A23 A24 Sample
allele % % size (N)
*23019515119

Allele

Haplotypes

References

Related Articles

Wikiwand AI