HLA-A36

HLA-A36
HLA-A36
(MHC Class I, A cell surface antigen)
	HLA-A36
About
Protein	transmembrane receptor/ligand
Structure	αβ heterodimer
Subunits	HLA-A*3601, β2-microglobulin
Subtypes
Subtype
Subtype	allele
A36	*3601
{{{cNick2}}}	*36{{{cAllele2}}}
{{{cNick3}}}	*36{{{cAllele3}}}
{{{cNick4}}}	*36{{{cAllele4}}}
	Alleles link-out to IMGT/HLA database at EBI

Proteintransmembrane receptor/ligand

Structureαβ heterodimer

SubunitsHLA-A*3601, β₂-microglobulin

Subtype

allele

HLA-A36 (A36) is a human leukocyte antigen serotype within HLA-A serotype group. The serotype is determined by the antibody recognition of α³⁶ subset of HLA-A α-chains. For A36, the alpha "A" chain are encoded by the HLA-A*36 allele group and the β-chain are encoded by B2M locus.^[1] This group currently is dominated by A*3601. A36 and A*36 are almost synonymous in meaning.

A36 is more common in Africa (North and East) and Central Asia. A36 is rare HLA-A allele group.

[1]

A*36	A36	A1	Sample
allele	%	%	size (N)
*3601	68	16	807

		freq
ref.	Population	(%)
	Kenya	6.6
^[3]	N. African (non-caucasian)	4.5
^[4]	Mossi (Burkina Faso)	3.8
^[5]	Beti (Cameroon)	3.7
^[3]	Mongolian	3.1
	Lusaka (Zambia)	3.1
^[3]	Harare Shona (Zimbabwe)	2.9
^[3]	Uyghurs (China)	2.6
^[5]	Bamileke (Cameroon)	2.6
^[6]	Amman (Jordan)	2.4
^[4]	Fulani	2.0
^[3]	Sweden	1.6
	Tswana (S. Africa)	1.2
	Kampala (Uganda)	1.2
^[3]	Spain	0.9
	Bubi (Equatorial Guinea)	0.5
^[3]	!Kung (San)	0.0
	Berber (Morocco)	0.0

HLA-A36

Distribution

References

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