HLA-A26

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HLA-A26
(MHC Class I, A cell surface antigen)
HLA-A26
About
Proteintransmembrane receptor/ligand
Structureαβ heterodimer
SubunitsHLA-A*2601, β2-microglobulin
Older namesA10
Subtypes
Subtype
allele
Available structures
A26.1 *2601
{{{cNick2}}} *26{{{cAllele2}}}
{{{cNick3}}} *26{{{cAllele3}}}
{{{cNick4}}} *26{{{cAllele4}}}
Rare alleles
Subtype
allele
Available structures
A26.2 *2602
A26.4 *2603
- *2605
Alleles link-out to IMGT/HLA database at EBI

HLA-A26 (A26) is a human leukocyte antigen serotype within HLA-A serotype group. The serotype is determined by the antibody recognition of α26 subset of HLA-A α-chains. For A26, the alpha "A" chain are encoded by the HLA-A*26 allele group and the β-chain are encoded by B2M locus.[1] This group currently is dominated by A*2601. A26 and A*26 are almost synonymous in meaning. A26 is a split antigen of the broad antigen serotype A10. A26 is a sister serotype of A25, A34, A43, and A66.

A26 is more common in West Pacific Rim (Taiwan to Hokkaido).

A26 recognition of some HLA A*26 gene products[2]
A*26 A26 A10 Sample
allele % % size (N)
*26019721730
*2602810  31
*2603688  38
*2605900  10

A26 reasonably good serotyping with no overt false recognition..

Distribution

Disease associations

References

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