HLA-A32

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Proteintransmembrane receptor/ligand
Structureαβ heterodimer
SubunitsHLA-A*3201, β2-microglobulin
Older names"A19"
HLA-A32
(MHC Class I, A cell surface antigen)
HLA-A32
About
Proteintransmembrane receptor/ligand
Structureαβ heterodimer
SubunitsHLA-A*3201, β2-microglobulin
Older names"A19"
Subtypes
Subtype
allele
Available structures
A19 *3201
{{{cNick2}}} *32{{{cAllele2}}}
{{{cNick3}}} *32{{{cAllele3}}}
{{{cNick4}}} *32{{{cAllele4}}}
Alleles link-out to IMGT/HLA database at EBI

HLA-A32 (A32) is a human leukocyte antigen serotype within HLA-A serotype group. The serotype is determined by the antibody recognition of α32 subset of HLA-A α-chains. For A32, the alpha "A" chain are encoded by the HLA-A*32 allele group and the β-chain are encoded by B2M locus.[1] This group currently is dominated by A*3201. A32 and A*32 are almost synonymous in meaning. A32 is a split antigen of the broad antigen serotype A19. A32 is a sister serotype of A29, A30, A31, A33, and A74.


A32 recognition of some HLA A*32 gene products[2]
A*32 A32 Sample
allele % size (N)
*3201943441

A32 Serotyping efficiency for the predominant allele is good. There are 16 known alleles that result in 15 isoforms of HLA-A32. One isoform may be poorly expressed.[3].

Distribution

Haplotypes

References

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