List of human microbiota

From Wikipedia, the free encyclopedia

Human microbiota are microorganisms (bacteria, viruses, fungi and archaea) found in a specific environment. They can be found in the stomach, intestines, skin, genitals and other parts of the body.[1] Various body parts have diverse microorganisms. Some microbes are specific to certain body parts and others are associated with many microbiomes. This article lists some of the species recognized as belonging to the human microbiome and focuses on the oral, vaginal, ovarian follicle, uterus and the male reproductive tract microbiota.

Categories of bacteria

The "reference" 70 kg human body is estimated to have around 39 trillion bacteria with a mass of about 0.2 kg.[2][3][4][5] These can be separated into about 10,000 microbial species, about 180 of the most studied is listed below here. However, these can broadly be put into three categories:[6]

Spheres or ball-shaped (cocci bacteria)

Cocci are usually round or spherical in shape. They can form clusters and are non-motile.[7] Examples include Staphylococcus aureus, Streptococcus pyogenes, and Neisseria gonorrhea.

Staphylococcus aureus

Rod-shaped bacteria (bacilli)

Bacilli usually have a rod or cylinder shape. Examples include Listeria, Salmonella typhimurium, Yersinia enterocolitica, and Escherichia coli.

Yersinia enterocolitica colonies growing on XLD agar plates
Escherichia coli
Color-enhanced scanning electron micrograph showing Salmonella typhimurium (red) invading cultured human cells

Spirals or helixes (spirochetes)

Spirochetes are usually spiral or corkscrew shaped and move using axial filament. Examples include Treponema pallidum and Leptospira borgpetersenii.[8]

[9] various forms of spirals

Eye

More information Binomial Name, Phylum ...
Binomial Name Phylum Location Pathogenicity Frequency/Abundance
Chlamydia pneumoniae Chlamydiota Eye Yes
Chlamydia trachomatis Chlamydiota Eye Yes
Haemophilus aegyptius Proteobacteria Eye
Haemophilus influenzae Proteobacteria Eye Sometimes
Moraxella spp Proteobacteria Eye Sometimes
Neisseria spp Proteobacteria Eye Only N. gonorrheae and N. meningitidis
Staphylococcus aureus Firmicutes Eye Sometimes
Staphylococcus epidermidis Firmicutes Eye
Streptococcus viridans Firmicutes Eye
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Mouth

The oral microbiota consists of all the microorganisms that exist in the mouth. It is the second largest of the human body and made of various bacteria, viruses, fungi and protozoa.[10] These organisms play an important role in oral and overall health. Anthony Van Leeuwenhoek was the first to view these organisms using a microscope he created.[10] The temperature and pH of saliva makes it conducive for bacteria to survive in the oral cavity. Bacteria in the oral cavity include Streptococcus mutans, Porphyromonas gingivalis, and Staphylococcus.[11] S. mutans is the main component of the oral microbiota.[11]

A healthy oral microbiome decreases oral infections and promotes a healthy gut microbiome. However, when disturbed, it can lead to gum inflammations and bad breath.[12] Dental plaque is formed when oral microorganisms form biofilms on the surfaces of teeth. Recommended practices to maintain a healthy oral microbiome include practicing good oral hygiene (brushing twice and flossing, replacing toothbrush often), eating healthy diet (food with little or no added sugars and ultra processed foods), drinking lots of water and taking probiotics.

More information Binomial Name, Phylum ...
Binomial Name Phylum Location Pathogenicity Frequency/Abundance
Abiotrophia spp[10] Mouth
Actinomyces spp[10] Actinomycetota Mouth
Actinomyces viscosus Actinomycetota Mouth
Actinomyces naeslundii Actinomycetota Mouth
Aggregatibacter actinomycetemcomitans Mouth
Arachnia propionica Mouth
Aspergillus spp[13] fungi Mouth
Atopobium spp[13] Actinomycetota Mouth
Aureobasidium spp[13] fungi Mouth
Bacterionema matruchotii

(Corynebacterium matruchotii)

Actinomycetota Gingiva
Bacteroides spp[13] Bacteroidota Mouth
Bacteroides gingivalis Bacteroidota Mouth
Bacteroides melaninogenicus Bacteroidota Mouth
Bergeyella spp[13] Bacteroidota Mouth
Bifidobacterium spp[10] Actinomycetota Mouth
Buchnera aphidicola Mouth
Bulleidia spp[13] Firmicutes Mouth
Campylobacter spp[10] Campylobacterota Mouth
Candida albicans[10] Ascomycota (fungi) Mouth Sometimes
Capnocytophaga spp[10] Bacteroidota Mouth
Cardiobacterium spp[13] Proteobacteria Mouth
Citrobacter freundii Throat
Cladosporium spp[10] fungi Mouth
Corynebacterium spp[10] Actinomycetota Mouth Only C. diphtheriae
Cryptococcus spp[13] fungi Mouth
Desulfobacter spp[10] Mouth
Desulfovibrio spp[10] Mouth
Dialister spp[13] Firmicutes Mouth
Eikenella corrodens[10] Proteobacteria Mouth Sometimes
Entamoeba gingivalis[10] Amoebozoa (eukaryote) Mouth
Enterococcus spp Firmicutes Mouth Sometimes
Eubacterium spp[10] Firmicutes Mouth
Fusarium spp[13] fungi Mouth
Fusobacterium spp[10] Fusobacteriota Mouth
Fusobacterium necrophorum Fusobacteriota Oropharynx
Fusobacterium nucleatum Fusobacteriota Mouth Sometimes
Gemella spp[13] Firmicutes Mouth
Gordonia spp Sputum
Granulicatella spp[13] Firmicutes Mouth
Haemophilus spp[10] Proteobacteria Mouth
Kingella spp[13] Proteobacteria Mouth
Lactobacillus spp[10] Firmicutes Mouth, Saliva No
Lautropia spp[13] Proteobacteria Mouth
Leptotrichia buccalis[10] Fusobacteriota Mouth
Methanobrevibacter oralis[13] Methanobacteriota (archaea) Mouth
Methanosarcina mazeii[13] Methanobacteriota (archaea) Mouth
Micrococcus spp Mouth
Mycoplasma spp Mouth
Mycoplasma orale Oropharynx
Mycobacterium chelonae Sputum
Neisseria spp[10] Proteobacteria Mouth Only N. gonorrheae and N. meningitidis
Oribacterium spp[13] Firmicutes Mouth
Peptococcus spp Mouth
Peptostreptococcus spp[10] Firmicutes Mouth
Porphyromonas gingivalis[1] Bacteroidota Mouth Sometimes
Prevotella spp[10] Bacteroidota Mouth Sometimes
Propionibacterium spp[10] Actinomycetota Mouth
Pseudoramibacter spp[10] Mouth
Rothia dentocariosa[10] Actinomycetota Mouth Occasionally
Selenomonas spp[10] Firmicutes Mouth
Simonsiella spp[10] Mouth
Staphylococcus aureus Firmicutes Mouth Sometimes
Staphylococcus epidermidis Firmicutes Mouth
Streptococcus anginosus[10] Firmicutes Oropharynx
Streptococcus mitis Firmicutes Mouth
Streptococcus mutans Firmicutes Teeth: dental plaque
Streptococcus oralis Firmicutes Teeth: dental plaque
Streptococcus sobrinus Firmicutes Teeth: dental plaque
Streptococcus viridans Firmicutes Mouth
Streptococcus constellatus Firmicutes Oropharynx
Streptococcus intermedius Firmicutes Oropharynx
Tannerella forsythia[1] Bacteroidota Mouth Sometimes
Torulopsis glabrata Mouth
Treponema denticola[10] Spirochetota Mouth
Trichomonas tenax[13] eukaryote Mouth
Veillonella spp[10] Firmicutes Mouth
Vibrio sputorum Mouth
Wolinella spp[10] Campylobacterota Mouth
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Respiratory System

More information Binomial Name, Phylum ...
Binomial Name Phylum Location Pathogenicity Frequency/Abundance
Acinetobacter spp Nasopharynx
Citrobacter freundii Sputum
Burkholderia cepacia complex Proteobacteria Lung
Campylobacter sputorum Nasopharynx
Candida albicans Ascomycota (fungi) Pharynx
Cardiobacterium spp Nose
Chlamydophila pneumoniae Chlamydiota Lung
Fusobacterium spp Fusobacteriota Lung
Haemophilus spp Proteobacteria Nasopharynx, lung
Hemophilus influenzae Proteobacteria Mucous membranes Sometimes
Haemophilus parainfluenzae Proteobacteria Pharynx
Haemophilus paraphrophilus Proteobacteria Pharynx
Kingella spp Proteobacteria Upper respiratory tract
Kingella kingae Proteobacteria Upper respiratory tract
Moraxella spp Proteobacteria Nasopharynx
Moraxella catarrhalis Proteobacteria Nasopharynx
Mycoplasma pneumoniae Respiratory epithelium
Neisseria spp Proteobacteria Nasopharynx
Neisseria cinerea Proteobacteria Nasopharynx
Neisseria elongata Proteobacteria Pharynx
Neisseria gonorrhoeae Proteobacteria Pharynx[citation needed] Yes
Neisseria lactamica Proteobacteria Nasopharynx
Neisseria meningitidis Proteobacteria Nasopharynx Yes
Neisseria mucosa Proteobacteria Nasopharynx
Neisseria sicca Proteobacteria Nasopharynx
Peptococcus spp Upper respiratory tract
Peptostreptococcus spp Firmicutes Pharynx
Pseudomonas spp Proteobacteria Lung
Pseudomonas aeruginosa Proteobacteria Lung Yes
Selenomonas sputigena Firmicutes Nasopharynx
Staphylococcus aureus Firmicutes Nose Sometimes
Streptobacillus spp Throat, nasopharynx
Streptococcus spp Firmicutes Lung
Streptococcus pyogenes Firmicutes Upper respiratory tract
Streptococcus pneumoniae Firmicutes Nasopharynx Sometimes
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Gastrointestinal Tract

More information Binomial Name, Phylum ...
Binomial Name Phylum Location Pathogenicity Frequency/Abundance
Achromobacter spp Large intestine, small intestine
Acidaminococcus fermentans Large intestine
Acinetobacter calcoaceticus Large intestine
Actinomyces spp Actinomycetota Small and large intestine
Aeromonas spp Large intestine, small intestine
Akkermansia muciniphilia[1] Verrucomicrobia Large intestine
Anaerobiospirillum spp Large intestine
Alcaligenes faecalis Large intestine, small intestine
Asteroleplasma[14] GI tract
Bacillus spp Firmicutes Large intestine
Bacteroides spp[1] Bacteroidota GI tract
Bacteroides fragilis Bacteroidota Large intestine
Bacteroides melaninogenicus Bacteroidota Large intestine
Bifidobacterium spp[1] Actinomycetota Large intestine, feces No
Butyriviberio fibrosolvens Large intestine
Campylobacter spp Campylobacterota Large intestine
Clostridium spp[1] Firmicutes Large intestine, small intestine
Clostridium sordellii Firmicutes Stomach, small intestine, large intestine
Dialister[14] Firmicutes GI tract
Escherichia coli[1] Proteobacteria GI tract Sometimes
Enterococcus spp[1] Firmicutes GI tract Sometimes
Eubacterium spp Firmicutes GI tract
Faecalibacterium spp[1] Firmicutes Large intestine, small intestine
Flavobacterium spp Large intestine, small intestine
Fusobacterium spp Fusobacteriota GI tract
Helicobacter pylori[1] Campylobacterota Stomach Yes
Lactobacillus spp Firmicutes Intestines
Megasphera[14] Firmicutes GI tract
Methanobrevibacter smithii[1] Methanobacteriota (archaea) Intestines No
Morganella morganii Intestines
Mycobacteria spp Actinomycetota Large intestine, small intestine
Mycoplasma spp Large intestine, small intestine
Paraprevotella[14] Bacteroidota Large intestine
Peptococcus spp Large intestine
Peptostreptococcus spp Firmicutes GI tract
Phascolarctobacterium[14] GI tract
Propionibacterium spp Actinomycetota Large intestine
Providencia spp Large intestine
Pseudomonas aeruginosa Proteobacteria Large intestine, small intestine
Roseburia spp Large intestine
Ruminococcus spp Firmicutes Large intestine
Ruminococcus bromii Large intestine
Sarcina spp Large intestine
Streptococcus anginosus Firmicutes GI tract
Streptococcus viridans Firmicutes Large intestine, small intestine
Succinovibrio[14] GI tract
Sutterella[14] GI tract
Veillonella spp[1] Firmicutes Large Intestine
Vibrio spp Large intestine, small intestine
Yersinia enterocolitica Large intestine
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Skin

More information Binomial Name, Phylum ...
Binomial Name Phylum Location Pathogenicity Frequency/Abundance
Acinetobacter spp Skin
Bacillus spp Firmicutes Skin
Candida albicans Ascomycota (fungi) Skin
Candida parapsilosis Ascomycota (fungi) Skin
Corynebacterium spp Actinomycetota Skin
Corynebacterium parvum Actinomycetota Skin
Cutibacterium acnes Actinomycetota Skin
Demodex folliculorum Skin
Enterobacter cloacae Skin
Epidermophyton floccosum Skin
Malassezia ovale Skin
Micrococcus luteus Skin
Micrococcus spp Skin
Mycobacterium spp Actinomycetota Skin
Neisseria spp Proteobacteria Skin
Peptostreptococcus spp Firmicutes Skin
Propionibacterium spp Actinomycetota Skin
Pseudomonas aeruginosa Proteobacteria Skin Mostly
Sarcina spp Skin
Staphylococcus aureus Firmicutes Skin Sometimes
Staphylococcus epidermidis Firmicutes Skin Sometimes, mostly not
Staphylococcus haemolyticus Firmicutes Skin
Streptococcus viridans Firmicutes Skin
Trichophyton spp Skin
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Female Reproductive Tract

The vaginal microbiota is shaped by puberty, pregnancy and menopause. Vaginal microbiota including some Lactobacillus species protect the vagina from harmful pathogens.[15] They convert glucose to lactic acid and this acidic environment kills harmful pathogens. The vaginal microbiota in pregnancy varies markedly during the entire time of gestation. The species and diversity of the

microorganisms may be related to the various levels of hormones during pregnancy. Vaginal flora can be transmitted to babies during birth. Vaginal dysbiosis can lead to vaginal infections like bacterial vaginosis which makes one relatively susceptible to sexually transmitted diseases. Good personal hygiene and probiotics promote a healthy vaginal microbiota.[16]

The healthy uterine microbiome has been identified and over 278 genera have been sequenced. Bacteria species like Fusobacterium are typically found in the uterus.[17] Although Lactobacillus may be beneficial in the vagina, "increased levels in the uterus through a breach in the cervical barrier" may be harmful to the uterus.[18]

The ovarian follicle microbiome has been studied using standard culturing techniques. It has been associated with the outcomes of assisted reproductive technologies and birth outcomes. Positive outcomes are related to the presence of Lactobacillus spp while the presence of Propionibacterium and Actinomyces were related to negative outcomes. The microbiome can vary from one ovary to the other. Studies are ongoing in the further identification of those bacteria present.[18]

More information Binomial Name, Phylum ...
Binomial Name Phylum Location Pathogenicity Frequency/Abundance
Acinetobacter spp Anterior urethra
Bacteroides spp Bacteroidota External genitalia
Candida albicans Ascomycota (fungi) Anterior urethra, external genitalia Sometimes
Enterobacteriaceae Anterior urethra, external genitalia
Gardnerella vaginalis[1] Vagina
Lactobacillus spp.[1] Firmicutes Vagina
Mycoplasma hominis[1] Vagina
Prevotella spp.[1] Bacteroidota Vagina
Streptococcus viridans Firmicutes Anterior urethra, external genitalia
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Male reproductive tract

The microbiome present in seminal fluid has been evaluated. Using traditional culturing techniques the microbiome differs between men who have acute prostatitis and those who have chronic prostatitis. Identification of the seminal fluid microbiome has become one of the diagnostic tools used in treating infertility in men that do not display symptoms of infection or disease. The taxa Pseudomonas, Lactobacillus, and Prevotella display a negative effect on the quality of sperm. The presence of Lactobacillus spp in semen samples is associated with a very high normal sperm count.[18]

More information Binomial Name, Phylum ...
Binomial Name Phylum Location Pathogenicity Frequency/Abundance
Acinetobacter spp Anterior urethra
Bacteroides spp Bacteroidota External genitalia
Candida albicans Ascomycota (fungi) Anterior urethra, external genitalia Sometimes
Enterobacteriaceae Anterior urethra, external genitalia
Streptococcus viridans Firmicutes Anterior urethra, external genitalia
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See also

Other lists of the human body's contents and building bricks

References

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