YWHAB

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

14-3-3 protein beta/alpha is a protein that in humans is encoded by the YWHAB gene.[5]

PDBOrtholog search: PDBe RCSB
AliasesYWHAB, GW128, HEL-S-1, HS1, KCIP-1, YWHAA, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
Quick facts Available structures, PDB ...
YWHAB
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesYWHAB, GW128, HEL-S-1, HS1, KCIP-1, YWHAA, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
External IDsOMIM: 601289; MGI: 1891917; HomoloGene: 20724; GeneCards: YWHAB; OMA:YWHAB - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_139323
NM_003404

NM_018753

RefSeq (protein)

NP_003395
NP_647539

NP_061223

Location (UCSC)Chr 20: 44.89 – 44.91 MbChr 2: 163.84 – 163.86 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse
Close

Function

This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene.[6]

Interactions

YWHAB has been shown to interact with:

See also

References

Further reading

Related Articles

Wikiwand AI