Wee1-like protein kinase

WEE1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1X8B, 2IN6, 2IO6, 2Z2W, 3BI6, 3BIZ, 3CQE, 3CR0
Identifiers
Aliases	WEE1, WEE1A, WEE1hu, WEE1 G2 checkpoint kinase
External IDs	OMIM: 193525; MGI: 103075; HomoloGene: 31152; GeneCards: WEE1; OMA:WEE1 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	9,593,457 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	109,742,493 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; skin of thigh; ; mucosa of paranasal sinus; ; tail of epididymis; ; gastric mucosa; ; buccal mucosa cell; ; embryo; ; ganglionic eminence; ; bronchial epithelial cell; ; skin of abdomen;
	Top expressed in
	decidua; ; gastrula; ; primitive streak; ; cumulus cell; ; parotid gland; ; endocardial cushion; ; vas deferens; ; pontine nuclei; ; maxillary prominence; ; mandibular prominence;
	More reference expression data
	n/a
Gene ontology
Molecular function	metal ion binding; nucleotide binding; protein tyrosine kinase activity; protein kinase activity; transferase activity; magnesium ion binding; non-membrane spanning protein tyrosine kinase activity; ATP binding; protein binding; kinase activity;
Cellular component	nucleolus; nucleoplasm; cytoplasm; nucleus;
Biological process	cell cycle; neuron projection morphogenesis; establishment of cell polarity; cell division; G2/M transition of mitotic cell cycle; microtubule cytoskeleton organization; peptidyl-tyrosine phosphorylation; protein phosphorylation; phosphorylation; mitotic cell cycle; G1/S transition of mitotic cell cycle; negative regulation of G1/S transition of mitotic cell cycle; mitotic cell cycle checkpoint signaling;
	Sources:Amigo / QuickGO
Orthologs
	7465
	22390
	ENSG00000166483
	ENSMUSG00000031016
	P30291
	P47810
	NM_001143976; NM_003390
	NM_009516; NM_001355058
	NP_001137448; NP_003381
	NP_033542; NP_001341987
	Wikidata
View/Edit Human	View/Edit Mouse

PDBOrtholog search: PDBe RCSB

AliasesWEE1, WEE1A, WEE1hu, WEE1 G2 checkpoint kinase

External IDsOMIM: 193525; MGI: 103075; HomoloGene: 31152; GeneCards: WEE1; OMA:WEE1 - orthologs

Chr.Chromosome 11 (human)^[1]

WEE1 homolog (S. pombe), also known as WEE1, is a protein which in humans is encoded by the WEE1 gene.^[5]

[1]

[2]

[3]

[4]

[5]

v t e Enzymes
Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Diffusion-limited enzyme Cofactor Enzyme catalysis
Regulation	Allosteric regulation Cooperativity Enzyme inhibitor Enzyme activator
Classification	EC number Enzyme superfamily Enzyme family List of enzymes
Kinetics	Enzyme kinetics Eadie–Hofstee diagram Hanes–Woolf plot Lineweaver–Burk plot Michaelis–Menten kinetics
Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list) EC7 Translocases (list)

Wee1-like protein kinase

Interactions

References

Further reading

External links

Related Articles

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