AGTR2

AliasAGTR2

IDs externesOMIM: 300034 MGI: 87966 HomoloGene: 20172 GeneCards: AGTR2

Chr.Chromosome X^[1]

Fin116,174,974 bp^[1]

AGTR2
Identifiants
Alias	AGTR2
IDs externes	OMIM: 300034 MGI: 87966 HomoloGene: 20172 GeneCards: AGTR2
Position du gène (humain) Chr. Chromosome X[1] Locus Xq23 Début 116,170,744 bp[1] Fin 116,174,974 bp[1]
Position du gène (souris) Chr. X chromosome (souris)[2] Locus X A2|X 16.71 cM Début 21,350,783 bp[2] Fin 21,355,403 bp[2]
Expression génique Bgee Humain Souris (orthologue) Fortement exprimé dans muscle lisse tibia lobe inférieur du poumon cartilage tissue left uterine tube pleura viscéral poumon droit upper lobe of lung upper lobe of left lung artère temporale superficielle Fortement exprimé dans derme efferent ductule canal déférent fœtus humain ganglion cervical supérieur artère carotide interne crête génitale artère carotide externe cordon ombilical corneal stroma Plus de données d'expression de référence BioGPS Plus de données d'expression de référence
Gene Ontology Fonction moléculaire signal transducer activity receptor antagonist activity peptide hormone binding G protein-coupled receptor activity liaison protéique angiotensin type II receptor activity transcription factor binding Composant cellulaire integral component of membrane membrane perinuclear region of cytoplasm membrane plasmique integral component of plasma membrane région extracellulaire Processus biologique regulation of metanephros size positive regulation of metanephric glomerulus development intracellular signal transduction kidney morphogenesis regulation of apoptotic process positive regulation of branching involved in ureteric bud morphogenesis positive regulation of nitric-oxide synthase activity transduction de signal dopamine biosynthetic process positive regulation of nitric oxide biosynthetic process negative regulation of norepinephrine secretion cellular sodium ion homeostasis renin-angiotensin regulation of aldosterone production cellular response to dexamethasone stimulus développement cérébral angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure brain renin-angiotensin system regulation of blood pressure kidney development negative regulation of icosanoid secretion positive regulation of extrinsic apoptotic signaling pathway regulation of systemic arterial blood pressure by circulatory renin-angiotensin aldosterone secretion G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger positive regulation of cell population proliferation régulation positive de la transcription dépendante de l'ADN negative regulation of blood vessel endothelial cell migration negative regulation of neurotrophin TRK receptor signaling pathway response to organonitrogen compound cerebellar cortex development negative regulation of fibroblast proliferation blood vessel remodeling cell growth involved in cardiac muscle cell development negative regulation of heart rate negative regulation of cell growth positive regulation of phosphoprotein phosphatase activity Comportement exploratoire réponse inflammatoire positive regulation of renal sodium excretion cell surface receptor signaling pathway nitric oxide mediated signal transduction angiotensin-activated signaling pathway extracellular negative regulation of signal transduction vasodilatation blood vessel diameter maintenance G protein-coupled receptor signaling pathway regulation of protein import into nucleus negative regulation of signaling receptor activity Sources:Amigo / QuickGO
Orthologues Espèces Homme Souris Entrez 186 11609 Ensembl ENSG00000180772 ENSMUSG00000068122 UniProt P50052 P35374 RefSeq (mRNA) NM_000686 NM_001385624 NM_007429 RefSeq (protéine) NP_000677 NP_031455 Localisation (UCSC) Chr X: 116.17 – 116.17 Mb Chr X: 21.35 – 21.36 Mb Publication PubMed [3] [4]
Wikidata
Voir/Editer Humain Voir/Editer Souris

L'AGTR2 est un gène du chromosome X humain aussi connu sous les noms de AT2, ATGR2 ou MRX88^[5].