| 2026 Game Log: 52–36 (Home: 31–13; Away: 21–23) |
March/April: 18–12 (Home: 8–4; Away: 10–8)
| # | Date | Opponent | Score | Win | Loss | Save | Venue | Attendance | Record | Streak/
Box |
| 1 | March 26 | @ Cardinals | 7–9 | O'Brien (1–0) | Cleavinger (0–1) | Stanek (1) | Busch Stadium | 45,037 | 0–1 | L1 |
| 2 | March 28 | @ Cardinals | 5–6 (10) | Stanek (1–0) | Jax (0–1) | — | Busch Stadium | 25,951 | 0–2 | L2 |
| 3 | March 29 | @ Cardinals | 11–7 | Matz (1–0) | May (0–1) | — | Busch Stadium | 27,653 | 1–2 | W1 |
| 4 | March 30 | @ Brewers | 3–2 | Cleavinger (1–0) | Megill (0–1) | Kelly (1) | American Family Field | 20,022 | 2–2 | W2 |
| 5 | March 31 | @ Brewers | 2–6 | Woodruff (1–0) | McClanahan (0–1) | — | American Family Field | 20,010 | 2–3 | L1 |
| 6 | April 1 | @ Brewers | 2–8 | Ashby (2–0) | Jax (0–2) | — | American Family Field | 21,949 | 2–4 | L2 |
| 7 | April 3 | @ Twins | 4–10 | Funderburk (1–1) | Kelly (0–1) | — | Target Field | 36,042 | 2–5 | L3 |
| 8 | April 4 | @ Twins | 7–1 | Matz (2–0) | Abel (0–2) | — | Target Field | 15,256 | 3–5 | W1 |
| 9 | April 5 | @ Twins | 4–1 (10) | Baker (1–0) | Topa (0–1) | Kelly (2) | Target Field | 13,069 | 4–5 | W2 |
| 10 | April 6 | Cubs | 6–4 | Kelly (1–1) | Taillon (0–1) | Baker (1) | Tropicana Field | 25,114 | 5–5 | W3 |
| 11 | April 7 | Cubs | 2–9 | Assad (1–0) | Englert (0–1) | — | Tropicana Field | 21,377 | 5–6 | L1 |
| 12 | April 8 | Cubs | 2–6 | Rea (1–0) | Boyle (0–1) | — | Tropicana Field | 20,483 | 5–7 | L2 |
| 13 | April 10 | Yankees | 5–3 | Matz (3–0) | Gil (0–1) | Baker (2) | Tropicana Field | 20,511 | 6–7 | W1 |
| 14 | April 11 | Yankees | 5–4 (10) | Sulser (1–0) | Bednar (0–2) | — | Tropicana Field | 21,620 | 7–7 | W2 |
| 15 | April 12 | Yankees | 5–4 | Rasmussen (1–0) | Schlittler (2–1) | Englert (1) | Tropicana Field | 20,796 | 8–7 | W3 |
| 16 | April 14 | @ White Sox | 8–5 | McClanahan (1–1) | Schultz (0–1) | Baker (3) | Rate Field | 14,648 | 9–7 | W4 |
| 17 | April 15 | @ White Sox | 8–3 | Scholtens (1–0) | Burke (0–2) | — | Rate Field | 10,193 | 10–7 | W5 |
| 18 | April 16 | @ White Sox | 5–3 | Kelly (2–1) | Domínguez (1–2) | Baker (4) | Rate Field | 10,128 | 11–7 | W6 |
| 19 | April 17 | @ Pirates | 1–5 | Chandler (1–1) | Martinez (0–1) | — | PNC Park | 24,198 | 11–8 | L1 |
| 20 | April 18 | @ Pirates | 8–7 (13) | Jax (1–2) | Ramírez (2–1) | Gómez (1) | PNC Park | 37,773 | 12–8 | W1 |
| 21 | April 19 | @ Pirates | 3–6 | Keller (2–1) | McClanahan (1–2) | — | PNC Park | 13,439 | 12–9 | L1 |
| 22 | April 20 | Reds | 1–6 | Lowder (3–1) | Scholtens (1–1) | — | Tropicana Field | 15,962 | 12–10 | L2 |
| 23 | April 21 | Reds | 6–12 | Burns (2–1) | Matz (3–1) | — | Tropicana Field | 14,749 | 12–11 | L3 |
| 24 | April 22 | Reds | 6–1 | Martinez (1–1) | Williamson (2–2) | — | Tropicana Field | 15,546 | 13–11 | W1 |
| 25 | April 24 | Twins | 6–2 | Rasmussen (2–0) | Bradley (3–1) | Baker (5) | Tropicana Field | 14,476 | 14–11 | W2 |
| 26 | April 25 | Twins | 6–1 | McClanahan (2–2) | Ober (2–1) | ― | Tropicana Field | 17,014 | 15–11 | W3 |
| 27 | April 26 | Twins | 4–2 | Scholtens (2–1) | Woods Richardson (0–4) | Baker (6) | Tropicana Field | 17,618 | 16–11 | W4 |
| 28 | April 27 | @ Guardians | 3–2 | Matz (4–1) | Gaddis (0–1) | Baker (7) | Progressive Field | 18,029 | 17–11 | W5 |
| 29 | April 28 | @ Guardians | 1–0 | Martinez (2–1) | Bibee (0–4) | Sulser (1) | Progressive Field | 16,213 | 18–11 | W6 |
| 30 | April 29 | @ Guardians | 1–3 | Williams (5–1) | Rasmussen (2–1) | Smith (7) | Progressive Field | 14,196 | 18–12 | L1 |
|
May: 18–8 (Home: 13–2; Away: 5–6)
| # | Date | Opponent | Score | Win | Loss | Save | Stadium | Attendance | Record | Streak/
Box |
| 31 | May 1 | Giants | 3–0 | McClanahan (3–2) | Ray (2–4) | Baker (8) | Tropicana Field | 13,330 | 19–12 | W1 |
| 32 | May 2 | Giants | 5–1 | Scholtens (3–1) | Roupp (5–2 | — | Tropicana Field | 21,973 | 20–12 | W2 |
| 33 | May 3 | Giants | 2–1 (10) | Seymour (1–0) | Kilian (1–1) | — | Tropicana Field | 20,108 | 21–12 | W3 |
| 34 | May 4 | Blue Jays | 5–1 | Martinez (3–1) | Lauer (1–4) | Baker (9) | Tropicana Field | 11,263 | 22–12 | W4 |
| 35 | May 5 | Blue Jays | 4–3 | Legumina (1–1) | Rogers (1–2) | Sulser (2) | Tropicana Field | 11,217 | 23–12 | W5 |
| 36 | May 6 | Blue Jays | 3–0 | McClanahan (4–2) | Corbin (1–1) | Seymour (1) | Tropicana Field | 11,275 | 24–12 | W6 |
| 37 | May 7 | @ Red Sox | 8–4 | Bigge (1–0) | Bennett (0–1) | — | Fenway Park | 33,961 | 25–12 | W7 |
| 38 | May 8 | @ Red Sox | 0–2 | Early (3–2) | Scholtens (3–2) | Chapman (8) | Fenway Park | 35,052 | 25–13 | L1 |
| ― | May 9 | @ Red Sox | Postponed due to rain. Makeup date July 17.[5] |
| 39 | May 10 | @ Red Sox | 4–1 | Martinez (4–1) | Tolle (1–2) | Baker (10) | Fenway Park | 33,489 | 26–13 | W1 |
| 40 | May 11 | @ Blue Jays | 8–5 | Rasmussen (3–1) | Gausman (2–3) | Baker (11) | Rogers Centre | 39,336 | 27–13 | W2 |
| 41 | May 12 | @ Blue Jays | 7–6 (10) | Seymour (2–0) | Fisher (2–1) | Cleavinger (1) | Rogers Centre | 41,265 | 28–13 | W3 |
| 42 | May 13 | @ Blue Jays | 3–5 (10) | Hoffman (2–2) | Brooks (0–1) | — | Rogers Centre | 40,119 | 28–14 | L1 |
| 43 | May 15 | Marlins | 7–2 | Scholtens (4–2) | Junk (2–4) | — | Tropicana Field | 14,919 | 29–14 | W1 |
| 44 | May 16 | Marlins | 5–10 (10) | Fairbanks (1–2) | Bigge (1–1) | — | Tropicana Field | 19,673 | 29–15 | L1 |
| 45 | May 17 | Marlins | 6–3 | Rasmussen (4–1) | Pérez (2–6) | Baker (12) | Tropicana Field | 16,788 | 30–15 | W1 |
| 46 | May 18 | Orioles | 16–6 | McClanahan (5–2) | Rogers (2–5) | — | Tropicana Field | 13,633 | 31–15 | W2 |
| 47 | May 19 | Orioles | 4–1 | Kelly (3–1) | Bradish (2–6) | Baker (13) | Tropicana Field | 13,956 | 32–15 | W3 |
| 48 | May 20 | Orioles | 5–3 | Scholtens (5–2) | Nunez (2–1) | Seymour (2) | Tropicana Field | 11,846 | 33–15 | W4 |
| 49 | May 22 | @ Yankees | 4–2 | Seymour (3–0) | Hill (0–2) | Baker (14) | Yankee Stadium | 41,358 | 34–15 | W5 |
| ― | May 23 | @ Yankees | Postponed due to rain. Makeup date September 22.[6] |
| 50 | May 24 | @ Yankees | 0–2 | Hill (1–2) | Kelly (3–2) | — | Yankee Stadium | 41,396 | 34–16 | L1 |
| 51 | May 25 | @ Orioles | 7–9 (13) | Enns (3–0) | Scholtens (5–3) | — | Camden Yards | 22,388 | 34–17 | L2 |
| 52 | May 26 | @ Orioles | 1–6 | Baz (2–5) | Jax (1–3) | — | Camden Yards | 11,878 | 34–18 | L3 |
| 53 | May 27 | @ Orioles | 2–11 | Gibson (1–0) | Matz (4–2) | — | Camden Yards | 16,317 | 34–19 | L4 |
| 54 | May 29 | Angels | 8–5 | Martinez (5–1) | Zeferjahn (2–3) | Baker (15) | Tropicana Field | 18,706 | 35–19 | W1 |
| 55 | May 30 | Angels | 3–14 | Detmers (2–5) | Rasmussen (4–2) | — | Tropicana Field | 22,480 | 35–20 | L1 |
| 56 | May 31 | Angels | 5–2 | McClanahan (6–2) | Kochanowicz (2–4) | Baker (16) | Tropicana Field | 16,589 | 36–20 | W1 |
|
June: 13–13 (Home: 10–6; Away: 3–7)
| # | Date | Opponent | Score | Win | Loss | Save | Stadium | Attendance | Record | Streak/
Box |
| 57 | June 1 | Tigers | 9–10 | Holton (1–4) | Jax (1–4) | Vest (1) | Tropicana Field | 13,695 | 36–21 | L1 |
| 58 | June 2 | Tigers | 0–8 | Flaherty (1–7) | Matz (4–3) | De Jesus (1) | Tropicana Field | 14,010 | 36–22 | L2 |
| 59 | June 3 | Tigers | 2–7 | Melton (2–0) | Martinez (5–2) | — | Tropicana Field | 12,585 | 36–23 | L3 |
| 60 | June 5 | @ Marlins | 6–0 | Rasmussen (5–2) | Gusto (0–1) | — | LoanDepot Park | 10,312 | 37–23 | W1 |
| 61 | June 6 | @ Marlins | 3–4 | King (3–1) | McClanahan (6–3) | Zuber (1) | LoanDepot Park | 12,443 | 37–24 | L1 |
| 62 | June 7 | @ Marlins | 1–4 | Alcántara (5–4) | Cleavinger (1–2) | Bender (2) | LoanDepot Park | 14,525 | 37–25 | L2 |
| 63 | June 8 | Red Sox | 3–1 | Legumina (2–1) | Early (5–4) | Baker (17) | Tropicana Field | 14,579 | 38–25 | W1 |
| 64 | June 9 | Red Sox | 4–3 | Martinez (6–2) | Tolle (3–3) | Baker (18) | Tropicana Field | 15,503 | 39–25 | W2 |
| 65 | June 10 | Red Sox | 7–5 | Rasmussen (6–2) | Bennett (1–2) | Cleavinger (2) | Tropicana Field | 16,504 | 40–25 | W3 |
| 66 | June 12 | @ Angels | 3–4 | Aldegheri (2–1) | McClanahan (6–4) | Zeferjahn (2) | Angel Stadium | 37,023 | 40–26 | L1 |
| 67 | June 13 | @ Angels | 0–8 | Soriano (8–4) | Jax (1–5) | — | Angel Stadium | 34,030 | 40–27 | L2 |
| 68 | June 14 | @ Angels | 8–3 | Kelly (4–2) | Bachman (1–1) | — | Angel Stadium | 34,048 | 41–27 | W1 |
| 69 | June 15 | @ Dodgers | 3–4 | Hurt (2–1) | Matz (4–4) | Scott (8) | Dodger Stadium | 53,911 | 41–28 | L1 |
| 70 | June 16 | @ Dodgers | 0–1 | Wrobleski (8–2) | Rasmussen (6–3) | Scott (9) | Dodger Stadium | 49,070 | 41–29 | L2 |
| 71 | June 17 | @ Dodgers | 4–5 | Ohtani (7–2) | Kelly (4–3) | Vesia (3) | Dodger Stadium | 50,705 | 41–30 | L3 |
| 72 | June 19 | Nationals | 5–2 | Jax (2–5) | Mikolas (2–6) | Baker (19) | Tropicana Field | 17,134 | 42–30 | W1 |
| 73 | June 20 | Nationals | 3–4 | Parker (3–3) | Seymour (3–1) | Beeter (5) | Tropicana Field | 20,996 | 42–31 | L1 |
| 74 | June 21 | Nationals | 4–3 | Cleavinger (2–2) | Ribalta (0–1) | Kelly (3) | Tropicana Field | 21,054 | 43–31 | W1 |
| 75 | June 22 | Royals | 1–2 | Wacha (5–5) | Rasmussen (6–4) | Lange (6) | Tropicana Field | 11,298 | 43–32 | L1 |
| 76 | June 23 | Royals | 5–12 | Avila (3–3) | McClanahan (6–5) | — | Tropicana Field | 11,171 | 43–33 | L2 |
| 77 | June 24 | Royals | 5–3 | Jax (3–5) | Cameron (4–5) | Baker (20) | Tropicana Field | 11,857 | 44–33 | W1 |
| 78 | June 25 | Royals | 13–2 | Seymour (4–1) | Lugo (3–5) | — | Tropicana Field | 14,276 | 45–33 | W2 |
| 79 | June 26 | Diamondbacks | 6–1 | Martinez (7–2) | Gallen (3–7) | — | Tropicana Field | 12,972 | 46–33 | W3 |
| 80 | June 27 | Diamondbacks | 4–2 | Grove (1–0) | Cabrera (0–1) | Baker (21) | Tropicana Field | 17,562 | 47–33 | W4 |
| 81 | June 28 | Diamondbacks | 5–1 | Rasmussen (7–4) | Kelly (5–8) | — | Tropicana Field | 17,195 | 48–33 | W5 |
| 82 | June 30 | @ Royals | 10–4 | Jax (4–5) | Cameron (4–6) | — | Kauffman Stadium | 15,014 | 49–33 | W6 |
|
July: 3–3 (Home: 0–1; Away: 3–2) |
August: 0–0 (Home: 0–0; Away: 0–0) |
September: 0–0 (Home: 0–0; Away: 0–0) |
