Farletuzumab

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Farletuzumab
Monoclonal antibody
TypeWhole antibody
SourceHumanized
TargetFR-alpha
Clinical data
Routes of
administration
Intravenous injection
ATC code
  • none
Identifiers
CAS Number
ChemSpider
  • none
UNII
KEGG
Chemical and physical data
FormulaC6466H9928N1716O2020S42
Molar mass145371.06 g·mol−1
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Farletuzumab (MORAb-003) is a humanized monoclonal antibody[1] of IgG1/κ[2] which is being investigated for the treatment of ovarian cancer.[3][4]

This drug was developed by Morphotek, Inc.

It is targeted at folate receptor alpha (FRα) which is overexpressed in some cancers such as epithelial ovarian cancer (EOC) and non-small-cell lung carcinoma.[2]

Adverse effects

References

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