Fluspidine

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Other names[18F]-Fluspidine
CAS Number
PubChem CID
ChemSpider
Fluspidine
Clinical data
Other names[18F]-Fluspidine
Identifiers
  • 1'-benzyl-1-(2-(17F)fluoranylethyl)spiro[1H-2-benzofuran-3,4'-piperidine]
CAS Number
PubChem CID
ChemSpider
ChEMBL
Chemical and physical data
FormulaC21H24FNO
Molar mass325.427 g·mol−1
3D model (JSmol)
  • C1CN(CCC12C3=CC=CC=C3C(O2)CC[18F])CC4=CC=CC=C4
  • InChI=InChI=1S/C21H24FNO/c22-13-10-20-18-8-4-5-9-19(18)21(24-20)11-14-23(15-12-21)16-17-6-2-1-3-7-17/h1-9,20H,10-16H2/i22-1
  • Key:LDFPQKADFLEDQV-KVTPGWOSSA-N

Fluspidine is a fluorine-18 (18F) labeled radiotracer used in positron emission tomography (PET) scans to image σ1 (sigma-1) receptors in the brain and other tissues. Sigma-1 receptors are proteins involved in many neurological and psychiatric processes. They have been linked to pain modulation, psychosis, Alzheimer's disease, and depression.[1]

References

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