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Introduction

Cannabis sativa
Common hemp

Cannabis (/ˈkænəbɪs/ ⓘ) is a genus of flowering plants in the family Cannabaceae that is widely accepted as being indigenous to and originating from the continent of Asia. However, the number of species is disputed, with as many as three species being recognized: Cannabis sativa, C. indica, and C. ruderalis. Alternatively, C. ruderalis may be included within C. sativa, or all three may be treated as subspecies of C. sativa, or C. sativa may be accepted as a single undivided species.

The plant is also known as hemp, although this term is usually used to refer only to varieties cultivated for non-drug use. Hemp has long been used for fibre, seeds and their oils, leaves for use as vegetables, and juice. Industrial hemp textile products are made from cannabis plants selected to produce an abundance of fibre.

Cannabis also has a long history of being used for medicinal purposes, and as a recreational drug known by several slang terms, such as marijuana, pot or weed. Various cannabis strains have been bred, often selectively to produce high or low levels of tetrahydrocannabinol (THC), a cannabinoid and the plant's principal psychoactive constituent. Compounds such as hashish and hash oil are extracted from the plant. More recently, there has been interest in other cannabinoids like cannabidiol (CBD), cannabigerol (CBG), and cannabinol (CBN). (Full article...)

Medical cannabis, medicinal cannabis or medical marijuana (MMJ) includes cannabis products and cannabinoid molecules that are prescribed by physicians for their patients. The use of cannabis as medicine has a long history, but has not been as rigorously tested as other medicinal plants due to legal and governmental restrictions, resulting in limited research to define the safety and efficacy of using cannabis to treat diseases.

There is mixed and inconclusive evidence on the benefits of cannabis-based medicines, frequent mild adverse effects, and generally low-to-moderate quality of evidence. Cannabis-based medicines may offer modest relief for chronic, especially neuropathic, pain and slight improvements in function and sleep in chronic pain patients, but evidence is limited and inconsistent; mild harms may outweigh the benefit and placebo effects may influence trial outcomes. Recent clinical reviews have concluded that evidence remains insufficient to support the use of cannabis or cannabinoids for most medical indications, emphasizing that modest potential benefits must be weighed against established risks. (Full article...)

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Flowering Cannabis indica plant
Flowering Cannabis indica plant
Credit: Aleksander Sowa

Cannabis indica has a higher ratio of CBD:THC compared to Cannabis sativa. Cannabis strains with relatively high CBD:THC ratios are less likely to induce anxiety than vice versa. The effects of sativa are well known for its cerebral high, while indica is well known for its sedative effects which some prefer for night time use. Both types are used as medical cannabis. Indica plants are normally shorter and stockier than sativas. They have wide, deeply serrated leaves and a compact and dense flower cluster. The effects of indicas are predominantly physical and sedative.

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