Talk:Syphilis

This edit request by an editor with a conflict of interest has now been answered.

Hello, I have a conflict of interest as an employee of Truveta and therefore will not edit the article directly. I am requesting an independent editor’s review.

I propose adding a sentence summarizing a 2025 peer-reviewed study of syphilis incidence trends in the United States. The study does not evaluate Truveta itself; it uses real-world electronic health record data from multiple U.S. health systems that contribute data to Truveta. The results provide updated epidemiologic information consistent with the scope of the existing Epidemiology section.

Proposed sentence:

A 2025 cohort study using electronic health record data from multiple U.S. health systems contributing data to Truveta found that syphilis incidence among adults more than tripled between 2017 and mid-2022 before declining through late 2024, with declines concentrated in groups historically experiencing higher incidence (such as men, younger adults, individuals living with HIV, and individuals using HIV pre-exposure prophylaxis) and rising incidence among populations without documented traditional STI risk factors.^[1]

I suggest placing this sentence in the Epidemiology section, immediately after the existing discussion of rising U.S. syphilis rates in the 2000s–2020s.

Thank you for your consideration.

Lyolek25 (talk) 21:13, 11 December 2025 (UTC)

Not done: This is promotional closhund/talk/ 08:53, 25 December 2025 (UTC)

What if it's re-written to say this:

A cohort study using de-identified electronic health record data from multiple U.S. health systems reported that adult syphilis incidence rose substantially from 2017 through 2022 and then declined through 2024, with trends varying across demographic and clinical subgroups.^[1] Lyolek25 (talk) 22:37, 20 January 2026 (UTC)

The epidemiology section of this article claims an 8% to 58% untreated mortality rate, cited to a paper, however, upon double-checking, I noticed the 58% figure is not a mortality rate for syphilis, but rather the rate for autopsies where syphilis was the primary cause of death among patients who "had clinical, serological, or autopsy evidence of syphilis." The paper only has two mortality rate figures, 8% for females, and 17% for males. Apocalyte (talk) 04:17, 10 March 2026 (UTC)