AZD9272

AZD 9272
Identifiers
	IUPAC name 3-fluoro-5-[3-(5-fluoropyridin-2-yl)-1,2,4-oxadiazol-5-yl]benzonitrile;
CAS Number	327056-26-8 ;
PubChem CID	9838729;
IUPHAR/BPS	6439;
ChemSpider	8014449;
UNII	54SQ9B412I;
ChEMBL	ChEMBL2164551;
Chemical and physical data
Formula	C14H6F2N4O
Molar mass	284.226 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES N#Cc1cc(cc(F)c1)c1nc(no1)c1ncc(F)cc1;
	InChI InChI=1S/C14H6F2N4O/c15-10-1-2-12(18-7-10)13-19-14(21-20-13)9-3-8(6-17)4-11(16)5-9/h1-5,7H; Key:RBSPCALDSNXWEP-UHFFFAOYSA-N;

AZD 9272 is a drug which acts as a selective antagonist for the metabotropic glutamate receptor subtype mGluR5.^[1] It was unsuccessful in human trials as an analgesic,^[2] but continues to be widely used in research especially as its radiolabelled forms.^[3]^[4]^[5]^[6]

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Identifiers

IUPAC name 3-fluoro-5-[3-(5-fluoropyridin-2-yl)-1,2,4-oxadiazol-5-yl]benzonitrile
CAS Number	327056-26-8^Y
PubChem CID	9838729
IUPHAR/BPS	6439
ChemSpider	8014449
UNII	54SQ9B412I
ChEMBL	ChEMBL2164551
Chemical and physical data
Formula	C₁₄H₆F₂N₄O
Molar mass	284.226 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES N#Cc1cc(cc(F)c1)c1nc(no1)c1ncc(F)cc1
InChI InChI=1S/C14H6F2N4O/c15-10-1-2-12(18-7-10)13-19-14(21-20-13)9-3-8(6-17)4-11(16)5-9/h1-5,7H Key:RBSPCALDSNXWEP-UHFFFAOYSA-N