Ro67-4853

Ro67-4853
Identifiers
	IUPAC name butyl (9H-xanthene-9-carbonyl)carbamate;
CAS Number	302841-89-0;
PubChem CID	9949202;
IUPHAR/BPS	1387;
ChemSpider	8124813;
UNII	QM27L9Q3RZ;
CompTox Dashboard (EPA)	DTXSID70433240 ;
Chemical and physical data
Formula	C19H19NO4
Molar mass	325.364 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES c3cccc2c3Oc1ccccc1C2C(=O)NC(=O)OCCCC;
	InChI InChI=1S/C19H19NO4/c1-2-3-12-23-19(22)20-18(21)17-13-8-4-6-10-15(13)24-16-11-7-5-9-14(16)17/h4-11,17H,2-3,12H2,1H3,(H,20,21,22); Key:RQBUXEUMZZQUFY-UHFFFAOYSA-N;
	(verify)

Ro67-4853 is a drug used in scientific research, which acts as a selective positive allosteric modulator for the metabotropic glutamate receptor subtype mGluR₁.^[1]^[2]^[3] It was derived by modification of the simpler compound Ro01-6128, and has itself subsequently been used as a lead compound to develop a range of potent and selective mGluR₁ positive modulators.^[4]^[5]

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Identifiers


IUPAC name butyl (9H-xanthene-9-carbonyl)carbamate
CAS Number	302841-89-0
PubChem CID	9949202
IUPHAR/BPS	1387
ChemSpider	8124813
UNII	QM27L9Q3RZ
CompTox Dashboard (EPA)	DTXSID70433240
Chemical and physical data
Formula	C₁₉H₁₉NO₄
Molar mass	325.364 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES c3cccc2c3Oc1ccccc1C2C(=O)NC(=O)OCCCC
InChI InChI=1S/C19H19NO4/c1-2-3-12-23-19(22)20-18(21)17-13-8-4-6-10-15(13)24-16-11-7-5-9-14(16)17/h4-11,17H,2-3,12H2,1H3,(H,20,21,22) Key:RQBUXEUMZZQUFY-UHFFFAOYSA-N
(verify)