Encofosbuvir

Encofosbuvir
Clinical data
Trade names	英强布韦
Legal status
Legal status	Rx in China;
Identifiers
	IUPAC name [3-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-3-methyl-5-[[[[(2S)-1-oxo-1-propan-2-yloxypropan-2-yl]amino]-phenoxyphosphoryl]oxymethyl]oxolan-2-yl]-2,6-dioxopyrimidin-1-yl]methyl (2S)-2-(methoxycarbonylamino)-4-methylsulfanylbutanoate;
CAS Number	2232134-77-7;
PubChem CID	141522644;
UNII	82E4Q8WQV7;
Chemical and physical data
Formula	C30H42FN4O13PS
Molar mass	748.71 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C[C@]1(F)[C@@H](O[C@H](COP(OC2=CC=CC=C2)(N[C@H](C(OC(C)C)=O)C)=O)[C@H]1O)N3C(=O)N(COC([C@@H](NC(OC)=O)CCSC)=O)C(=O)C=C3;
	InChI InChI=1S/C30H42FN4O13PS/c1-18(2)46-25(38)19(3)33-49(42,48-20-10-8-7-9-11-20)45-16-22-24(37)30(4,31)27(47-22)34-14-12-23(36)35(29(34)41)17-44-26(39)21(13-15-50-6)32-28(40)43-5/h7-12,14,18-19,21-22,24,27,37H,13,15-17H2,1-6H3,(H,32,40)(H,33,42)/t19-,21-,22+,24+,27+,30+,49-/m0/s1; Key:GAHCKEWMXZYJAZ-VBWBMHESSA-N;

Trade names英强布韦

Legal status

Rx in China

CAS Number

2232134-77-7

PubChem CID

141522644

Encofosbuvir is an antiviral drug used to treat hepatitis C virus (HCV). In China, encofosbuvir is approved for use in combination with netanasvir for the treatment of adult patients with chronic HCV genotypes 1, 2, 3, or 6, who are either treatment-naive or have been previously treated with interferon.^[1]

[1]

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