PRE-084

PRE-084
Clinical data
ATC code	none;
Identifiers
	IUPAC name 2-morpholin-4-ylethyl 1-phenylcyclohexane-1-carboxylate;
CAS Number	138847-85-5 ;
PubChem CID	126402;
IUPHAR/BPS	6678;
ChemSpider	112335 ;
UNII	74BW8WG2MQ;
CompTox Dashboard (EPA)	DTXSID40160819 ;
Chemical and physical data
Formula	C19H27NO3
Molar mass	317.429 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES c1ccccc1C2(CCCCC2)C(=O)OCCN3CCOCC3;
	InChI InChI=1S/C19H27NO3/c21-18(23-16-13-20-11-14-22-15-12-20)19(9-5-2-6-10-19)17-7-3-1-4-8-17/h1,3-4,7-8H,2,5-6,9-16H2 ; Key:RQHKZUBCUZVZEF-UHFFFAOYSA-N ;
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PRE-084 is a sigma receptor agonist, selective for the σ₁ subtype. It has nootropic and antidepressant actions in animal studies, as well as antitussive and reinforcing effects.^[1]^[2]^[3]^[4]^[5] PRE-084 increases the expression of GDNF.^[6]

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