↑ Squires,Sally(2006年1月24日).“Weighing a Pill For Weight Loss”.Washington Post.https://www.washingtonpost.com/wp-dyn/content/article/2006/01/23/AR2006012301270.html2007年7月6日閲覧."While the Food and Drug Administration (FDA) still must approve the switch, the agency often follows the advice of its experts. If it does, Orlistat (xenical) -- currently sold only by prescription -- could be available over-the-counter (OTC) later this year. But it's important to know that the weight loss that's typical for users of the drug -- 5 to 10 percent of total weight -- will be less than many dieters expect. And many consumers may be put off by the drug's significant gastrointestinal side effects, including flatulence, diarrhea and anal leakage."
↑ “Frito-Lay Study: Olestra Causes "Anal Oil Leakage"”.Center for Science in the Public Interest.(1997年2月13日).http://www.cspinet.org/new/flaynal.html2007年7月7日閲覧."The Frito-Lay report states: "The anal oil leakage symptoms were observed in this study (3 to 9% incidence range above background), as well as other changes in elimination. ... Underwear spotting was statistically significant in one of two low level consumer groups at a 5% incidence above background." Despite those problems, the authors of the report concluded that olestra-containing snacks "should have a high potential for acceptance in the marketplace.""
↑ “The Word Is 'Leakage'. Accidents may happen with a new OTC diet drug.”.Newsweek.(2007年6月25日).http://www.msnbc.msn.com/id/19263093/site/newsweek/2007年6月21日閲覧."GlaxoSmithKline has a tip for people who decide to try Alli, the over-the-counter weight-loss drug it is launching with a multimillion-dollar advertising blitz—keep an extra pair of pants handy. That's because Alli, a lower-dose version of the prescription drug Xenical, could (cue the late-night talk-show hosts) make you soil your pants. But while Alli's most troublesome side effect, anal leakage, is sure to be good for a few laughs, millions of people who are desperate to take off weight may still decide the threat of an accident is worth it."
