GSK1702934A

GSK1702934A
Identifiers
	IUPAC name 3-[1-(5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-2-carbonyl)piperidin-4-yl]-1H-benzimidazol-2-one;
CAS Number	924377-85-5;
PubChem CID	16376051;
ChemSpider	10981314;
CompTox Dashboard (EPA)	DTXSID701336582 ;
Chemical and physical data
Formula	C22H25N3O2S
Molar mass	395.52 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C1CCC2=C(CC1)SC(=C2)C(=O)N3CCC(CC3)N4C5=CC=CC=C5NC4=O;
	InChI InChI=1S/C22H25N3O2S/c26-21(20-14-15-6-2-1-3-9-19(15)28-20)24-12-10-16(11-13-24)25-18-8-5-4-7-17(18)23-22(25)27/h4-5,7-8,14,16H,1-3,6,9-13H2,(H,23,27); Key:AXWRAIIIBRLXBP-UHFFFAOYSA-N;

GSK1702934A is a chemical compound which acts as an activator of the TRPC family of calcium channels, with selectivity for the TRPC3 and TRPC6 subtypes. It has been used to investigate the role of TRPC channels in heart function and regulation of blood pressure, as well as roles in the brain.^[1]^[2]^[3]^[4]

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Identifiers

IUPAC name 3-[1-(5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-2-carbonyl)piperidin-4-yl]-1H-benzimidazol-2-one
CAS Number	924377-85-5
PubChem CID	16376051
ChemSpider	10981314
CompTox Dashboard (EPA)	DTXSID701336582
Chemical and physical data
Formula	C₂₂H₂₅N₃O₂S
Molar mass	395.52 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES C1CCC2=C(CC1)SC(=C2)C(=O)N3CCC(CC3)N4C5=CC=CC=C5NC4=O
InChI InChI=1S/C22H25N3O2S/c26-21(20-14-15-6-2-1-3-9-19(15)28-20)24-12-10-16(11-13-24)25-18-8-5-4-7-17(18)23-22(25)27/h4-5,7-8,14,16H,1-3,6,9-13H2,(H,23,27) Key:AXWRAIIIBRLXBP-UHFFFAOYSA-N

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