Tetrahydrocannabiorcol

CAS Number

• 22972-65-2

PubChem CID

• 22805649

ChemSpider

• 18522304

UNII

• 5D633LAJ19

Tetrahydrocannabiorcol

Identifiers
IUPAC name (6aR,10aR)-3,6,6,9-tetramethyl-6a,7,8,10a-tetrahydrobenzo[c]chromen-1-ol
CAS Number	22972-65-2
PubChem CID	22805649
ChemSpider	18522304
UNII	5D633LAJ19
CompTox Dashboard (EPA)	DTXSID901336645
Chemical and physical data
Formula	C17H22O2
Molar mass	258.361 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC1=C[C@@H]2[C@@H](CC1)C(OC3=CC(=CC(=C23)O)C)(C)C
InChI InChI=1S/C17H22O2/c1-10-5-6-13-12(7-10)16-14(18)8-11(2)9-15(16)19-17(13,3)4/h7-9,12-13,18H,5-6H2,1-4H3/t12-,13-/m1/s1 Key:WIDIPARNVYRVNW-CHWSQXEVSA-N

Δ⁹-Tetrahydrocannabiorcol (Δ⁹-THCC, (C1)-Δ⁹-THC) is a phytocannabinoid found in Cannabis pollen.^[1] It is a homologue of THC and THCV with the alkyl side chain replaced by a smaller methyl group. Unlike THC and THCV, THCC has negligible affinity for the CB₁ and CB₂ cannabinoid receptors because of the smaller methyl group and does not have psychoactive effects as a result, but conversely it is significantly more potent than THC or THCV as an activator of the TRPA1 calcium channel which plays an important role in pain perception,^[2] and it has been shown to produce analgesic effects via activation of spinal TRPA1 channels.^[3][4] THCC was studied by Roger Adams as early as 1942.^[5]