ML-SI3

ML-SI3 is a chemical compound which acts as an "antagonist" (i.e. channel blocker) of the TRPML family of calcium channels, with greatest activity at the TRPML1 channel, although it also blocks the related TRPML2 and TRPML3 channels with lower affinity. It is used for research into the role of TRPML1 and its various functions in lysosomes and elsewhere in the body.^{[1][2][3][4][5][6][7]}

CAS Number

• 891016-02-7

PubChem CID

• 94784693

ChemSpider

• 20304221

CompTox Dashboard (EPA)

• DTXSID801336630

Quick facts Identifiers, CAS Number ...

ML-SI3

Identifiers
IUPAC name N-[(1S,2S)-2-[4-(2-methoxyphenyl)piperazin-1-yl]cyclohexyl]benzenesulfonamide
CAS Number	891016-02-7
PubChem CID	94784693
ChemSpider	20304221
CompTox Dashboard (EPA)	DTXSID801336630
Chemical and physical data
Formula	C23H31N3O3S
Molar mass	429.58 g·mol−1
3D model (JSmol)	Interactive image
SMILES COC1=CC=CC=C1N2CCN(CC2)[C@H]3CCCC[C@@H]3NS(=O)(=O)C4=CC=CC=C4
InChI InChI=1S/C23H31N3O3S/c1-29-23-14-8-7-13-22(23)26-17-15-25(16-18-26)21-12-6-5-11-20(21)24-30(27,28)19-9-3-2-4-10-19/h2-4,7-10,13-14,20-21,24H,5-6,11-12,15-18H2,1H3/t20-,21-/m0/s1 Key:OVTXOMMQHRIKGL-SFTDATJTSA-N

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