GS (nerve agent)
From Wikipedia, the free encyclopedia
 | |
| Names | |
|---|---|
| IUPAC name
2-[fluoro(methyl)phosphoryl]oxycyclopentane | |
| Other names
Cyclopentyl methylphosphonofluoridate | |
| Identifiers | |
3D model (JSmol) |
|
| ChemSpider | |
PubChem CID |
|
| |
| |
| Properties | |
| C6H12FO2P | |
| Molar mass | 166.132 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
| |
GS (IUPAC name: Cyclopentyl methylphosphonofluoridate), also known as G-agent S candidate No. 3 or EA-1246 (Edgewood Arsenal cryptonym), is an organophosphate nerve agent, part of a series of nerve agents "G-series".[1] It is a potent acetylcholinesterase inhibitor with properties similar to other nerve agents. GS is structurally a derivative of the nerve agent sarin, being closely structurally related to GP. The carbon-carbon bond angle makes it less persistent than sarin. It is a derivative of its acyclic equivalent, 3-pentanyl methylphosphonofluoridate.[2]
GS rapidly ages the acetylcholinesterase, exhibiting a rate approximately half that of soman and 60 times faster than its larger GF counterpart.[3][4] GS was the third candidate in a series of 6 other organophosphonates, in which the vast majority are cycloalkyl/alkyl methylphosphonofluoridates, with the exception of GS-7, a derivative of the pesticide monitor.[3]