HLA-B45
Human leukocyte antigen serotype
From Wikipedia, the free encyclopedia
HLA-B45 (B45) is an HLA-B serotype. The serotype identifies the B*45 gene-allele protein products of HLA-B.[1]
 | ||
| HLA-B (alpha)-β2MG with bound peptide | ||
major histocompatibility complex (human), class I, B45 | ||
| Alleles | B*4501, 4502 . . | |
| Structure (See HLA-B) | ||
| Shared data | ||
| Locus | chr.6 6p21.31 | |
B45 is a split antigen of the broad antigen B12, and is a sister type of B44. Gene products of 45 not 44
Serotype
Alleles
It was reported that a novel haplotype was found in Italian bone marrow donors. A2-CW*1601-B45- DRB1*1101-DRB3*0301-DQA1*0102-DQB1*0502. This haplotype indicates possible very recent ancestry from Africa, with the Cw*1601 and B45 components and also with the DR11-DQ5.2 component both extremely rare in Europe.[3]