HLA-B50

Human leukocyte antigen serotype From Wikipedia, the free encyclopedia

HLA-B50 (B50) is an HLA-B serotype. B50 is a split antigen from the B21 broad antigen, the sister serotype B49.[1] The serotype identifies the more common HLA-B*50 gene products.[2] (For terminology help see: HLA-serotype tutorial)

major histocompatibility complex (human), class I, B50
Alleles B*5001, B*5002,
Structure (See HLA-B)
Symbol(s) HLA-B
EBI-HLA B*5001
B*5002
Locus chr.6 6p21.31

Serotype

B50 and B21 serotype recognition of some more common HLA B*50 alleles[3]
B*50B50 B21Sample
allele%%size (N)
50018531700

The B*5002 by serotype definition is a B45 serotype.[4]

Allele distribution

HLA B*5001 frequencies
freq
ref.Population(%)
[5]Saudi Arabia Guraiat and Hail17.3
[5]Tunisia10.0
[5]Israel Arab Druse8.5
[5]Morocco Nador Metalsa (Berber)7.3
[5]Tunisia Tunis6.3
[5]Israel Ashkenazi and Non Ashkenazi Jews5.5
[5]Azores Terceira Island5.1
[5]Georgia Svaneti Svans3.8
[5]India North Delhi3.8
[5]Italy Bergamo3.6
[5]Georgia Tbilisi Kurds3.4
[5]Italy North (1)3.3
[5]Brazil Belo Horizonte3.2
[5]Madeira3.2
[5]Italy North Pavia3.1
[5]Portugal South3.1
[5]Oman3.0
[5]Georgia Tbilisi Georgians2.8
[5]Bulgaria2.7
[5]Azores Santa Maria and Sao Miguel2.6
[5]Spain Eastern Andalusia Gipsy2.5
[5]Sudanese2.5
[5]Czech Republic2.4
[5]Spain Eastern Andalusia2.4
[5]Spain Mallorca and Menorca2.2
[5]Burkina Faso Fulani2.0
[5]China Inner Mongolia2.0
[5]China North Han1.9
[5]India North Hindus1.9
[5]China Qinghai Hui1.8
[5]Jordan Amman1.7
[5]Russia Tuva (2)1.7
[5]Spain Catalonia Girona1.7
[5]Senegal Niokholo Mandenka1.6
[5]Guinea Bissau1.5
[5]India New Delhi1.5
[5]Croatia1.3
[5]Cuban Mulatto1.2
[5]France South East1.2
[5]Burkina Faso Rimaibe1.1
[5]Mali Bandiagara1.1
[5]Belgium1.0
[5]Ireland Northern1.0
[5]Ireland South1.0
[5]Italy Sardinia pop31.0
[5]South Africa Natal Tamil1.0
B*5002
[5]Morocco Nador Metalsa (Berber)4.3
[5]Portugal North1.1
[5]Portugal South1.0
[5]Madeira0.8
[5]Tunisia Tunis0.6

References

Related Articles

Wikiwand AI