FGF20

Protein From Wikipedia, the free encyclopedia

Fibroblast growth factor 20 is a protein which in humans is encoded by the FGF20 gene.[1]

Quick facts fibroblast growth factor 20, Identifiers ...
fibroblast growth factor 20
Identifiers
SymbolFGF20
NCBI gene26281
HGNC3677
OMIM605558
RefSeqNM_019851
UniProtQ9NP95
Other data
LocusChr. 8 p22
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StructuresSwiss-model
DomainsInterPro
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Function

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development,[2] cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was shown to be expressed in normal brain, particularly the cerebellum. The rat homolog is preferentially expressed in the brain and able to enhance the survival of midbrain dopaminergic neurons in vitro.[3]

References

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