Setastine
Chemical compound
From Wikipedia, the free encyclopedia
Setastine (Loderix) is an antihistamine used to treat allergies and rhinitis.[1][2]
| |
 | |
| Identifiers | |
|---|---|
| |
| CAS Number |
|
| PubChem CID | |
| ChemSpider | |
| UNII |
|
| CompTox Dashboard (EPA) | |
| Chemical and physical data | |
| Formula | C22H28ClNO |
| Molar mass | 357.92 g·mol−1 |
| 3D model (JSmol) | |
| |
Pharmacology
Pharmacodynamics
Setastine acts as a highly selective H1 receptor antagonist.[3] It has no anticholinergic, antiadrenergic, or antiserotonergic effects.
Pharmacokinetics
Setastine penetrates the blood-brain-barrier poorly so it is only mildly sedating compared to related molecules like diphenhydramine.[3]