2023 Antofagasta Challenger

Country	Player	Rank1	Seed
ARG	Juan Manuel Cerúndolo	91	1
CHI	Tomás Barrios Vera	114	2
CHI	Alejandro Tabilo	124	3
ARG	Genaro Alberto Olivieri	138	4
BOL	Hugo Dellien	141	5
ARG	Facundo Bagnis	144	6
ARG	Francisco Comesaña	150	7
ITA	Luciano Darderi	177	8

¹ Rankings are as of 11 September 2023.^[1]

The following players received wildcards into the singles main draw:

• Gonzalo Lama
• Juan Carlos Prado Ángelo
• Matías Soto

The following players received entry into the singles main draw as alternates:

• Tristan Boyer
• Viktor Durasovic
• Eduardo Ribeiro

The following players received entry from the qualifying draw:

• Pedro Boscardin Dias
• Tomás Farjat
• Gilbert Klier Júnior
• Facundo Mena
• Ignacio Monzón
• Pedro Sakamoto

• Camilo Ugo Carabelli def. Tristan Boyer 3–6, 6–1, 7–5.

• Boris Arias / Federico Zeballos def. Luciano Darderi / Murkel Dellien 5–7, 6–4, [10–8].