2023 Mexico City Open

Country	Player	Rank1	Seed
SUI	Marc-Andrea Hüsler	47	1
COL	Daniel Elahi Galán	89	2
ARG	Facundo Bagnis	100	3
AUS	James Duckworth	112	4
GER	Yannick Hanfmann	134	5
CHI	Alejandro Tabilo	162	6
BRA	Felipe Meligeni Alves	164	7
ITA	Luciano Darderi	173	8

• ¹ Rankings are as of 20 March 2023.^[1]

The following players received wildcards into the singles main draw:

• Nicolás Mejía
• Rodrigo Pacheco Méndez
• Bernard Tomic

The following player received entry into the singles main draw as an alternate:

• Thiago Agustín Tirante

The following players received entry from the qualifying draw:

• Térence Atmane
• Elmar Ejupovic
• Federico Gaio
• Dominik Koepfer
• Juan Ignacio Londero
• Maximilian Neuchrist

• Dominik Koepfer def. Thiago Agustín Tirante 2–6, 6–4, 6–2.

• Boris Arias / Federico Zeballos def. Evan King / Reese Stalder 7–5, 5–7, [10–2].