2025 Open Sopra Steria de Lyon

Country	Player	Rank1	Seed
ESP	Pablo Carreño Busta	99	1
DEN	Elmer Møller	112	2
FRA	Arthur Cazaux	113	3
FRA	Kyrian Jacquet	150	4
ARG	Juan Pablo Ficovich	152	5
IND	Sumit Nagal	170	6
FRA	Calvin Hemery	171	7
ARG	Marco Trungelliti	177	8

• ¹ Rankings are as of 26 May 2025.^[1]

The following players received wildcards into the singles main draw:

• Arthur Géa
• Tom Paris
• Clément Tabur

The following player received entry into the singles main draw as an alternate:

• Javier Barranco Cosano

The following players received entry from the qualifying draw:

• Nicolás Álvarez Varona
• Matthew Dellavedova
• Maxime Janvier
• Timo Legout
• Lucas Poullain
• Michael Vrbenský

• Marco Trungelliti def. Daniel Mérida 6–3, 4–6, 6–3.

• Hsu Yu-hsiou / Kaichi Uchida def. Luca Sanchez / Seita Watanabe 1–6, 6–3, [12–10].